{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tyurina YY"],"funding":["Russian academic excellence project","NIAID NIH HHS","NHLBI NIH HHS","NINDS NIH HHS","NCI NIH HHS","NIH","NIGMS NIH HHS"],"pagination":["93-107"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6714565"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["221"],"pubmed_abstract":["Aerobic life is based on numerous metabolic oxidation reactions as well as biosynthesis of oxygenated signaling compounds. Among the latter are the myriads of oxygenated lipids including a well-studied group of polyunsaturated fatty acids (PUFA) - octadecanoids, eicosanoids, and docosanoids. During the last two decades, remarkable progress in liquid-chromatography-mass spectrometry has led to significant progress in the characterization of oxygenated PUFA-containing phospholipids, thus designating the emergence of a new field of lipidomics, redox lipidomics. Although non-enzymatic free radical reactions of lipid peroxidation have been mostly associated with the aberrant metabolism typical of acute injury or chronic degenerative processes, newly accumulated evidence suggests that enzymatica"],"journal":["Chemistry and physics of lipids"],"pubmed_title":["\"Redox lipidomics technology: Looking for a needle in a haystack\"."],"pmcid":["PMC6714565"],"funding_grant_id":["NS061817","R01 GM113908","U19 AI068021","NS076511","R01 CA165065","HL114453-06","P30 CA010815","R01 NS076511","P01 HL114453","CA165065-06","U19AI068021","R01 NS061817"],"pubmed_authors":["Anthonymuthu T","Sparvero LJ","Sun W","He R","Tyurina YY","Khaitovich P","Kagan VE","Baynard ML","Vladimirov YA","Bayır H","Amoscato AA","Tyurin VA","Nesterova AM","Gabrilovich DI"],"additional_accession":[]},"is_claimable":false,"name":"\"Redox lipidomics technology: Looking for a needle in a haystack\".","description":"Aerobic life is based on numerous metabolic oxidation reactions as well as biosynthesis of oxygenated signaling compounds. Among the latter are the myriads of oxygenated lipids including a well-studied group of polyunsaturated fatty acids (PUFA) - octadecanoids, eicosanoids, and docosanoids. During the last two decades, remarkable progress in liquid-chromatography-mass spectrometry has led to significant progress in the characterization of oxygenated PUFA-containing phospholipids, thus designating the emergence of a new field of lipidomics, redox lipidomics. Although non-enzymatic free radical reactions of lipid peroxidation have been mostly associated with the aberrant metabolism typical of acute injury or chronic degenerative processes, newly accumulated evidence suggests that enzymatica","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Jul","modification":"2025-04-04T22:11:51.927Z","creation":"2019-09-05T07:02:37Z"},"accession":"S-EPMC6714565","cross_references":{"pubmed":["30928338"],"doi":["10.1016/j.chemphyslip.2019.03.012"]}}