biostudies-literatureConfer AMDivision of ChemistryJohns Hopkins UniversityNational Institute of General Medical SciencesNIGMS NIH HHS9576-9580https://www.ebi.ac.uk/biostudies/studies/S-EPMC6715289biostudies-literatureUnknown58(15)The synthesis of a new nonheme iron NO binding complex, [Fe^II(CH₃CN)(N3Py^2PhSEtCN)](BF₄)₂ (<b>1</b>), is reported. Complex <b>1</b>, which contains two sterically encumbering phenyl substituents, exhibits a high-spin (hs) Fe^II (<i>S</i> = 2) ground state in contrast to the <i>S</i> = 0 ground state for unsubstituted [Fe^II(CH₃CN)(N3PySEtCN)(BF₄)₂. Reaction of <b>1</b> with NO_(g) in CH₃CN yields an {FeNO}⁷ (<i>S</i> = ³/₂) complex <b>2</b>, which slowly decays at 25 °C with loss of NO^• to regenerate <b>1</b>. One-electron reduction of <b>2</b> with Cr(C₆H₆)₂ at -40 °C yields the metastaInorganic chemistryMononuclear, Nonheme, High-Spin {FeNO}^7/8 Complexes Supported by a Sterically Encumbered N₄S-Thioether Ligand.PMC6715289GM0747851566007R01 GM074785Confer AMMoenne-Loccoz PSabuncu SSiegler MAGoldberg DPfalseMononuclear, Nonheme, High-Spin {FeNO}^7/8 Complexes Supported by a Sterically Encumbered N₄S-Thioether Ligand.The synthesis of a new nonheme iron NO binding complex, [Fe^II(CH₃CN)(N3Py^2PhSEtCN)](BF₄)₂ (<b>1</b>), is reported. Complex <b>1</b>, which contains two sterically encumbering phenyl substituents, exhibits a high-spin (hs) Fe^II (<i>S</i> = 2) ground state in contrast to the <i>S</i> = 0 ground state for unsubstituted [Fe^II(CH₃CN)(N3PySEtCN)(BF₄)₂. Reaction of <b>1</b> with NO_(g) in CH₃CN yields an {FeNO}⁷ (<i>S</i> = ³/₂) complex <b>2</b>, which slowly decays at 25 °C with loss of NO^• to regenerate <b>1</b>. One-electron reduction of <b>2</b> with Cr(C₆H₆)₂ at -40 °C yields the metasta2019-01-01T00:00:00Z2019 Aug2025-04-22T10:39:13.471Z2020-10-29T17:07:43ZS-EPMC67152893132850110.1021/acs.inorgchem.9b01475