{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Degreef B"],"funding":["NIMH NIH HHS","National Institutes of Health"],"pagination":["108387"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6717681"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["326"],"pubmed_abstract":["<h4>Background</h4>Recently, the time resolution of microdialysis followed by a chemical separation for quantitative analysis has improved. The advent of faster microdialysis measurements promises to aid in behavioral research on awake animals. However, microdialysis with awake animals generally employs a fluidic commutator (swivel). The swivel's volume is inimical to the time resolution of the measurements.<h4>New method</h4>Animals can be housed in rotating cages so that the swivel is not required, but rotating operant chambers are not available. Here we describe the design and construction of a rotating operant chamber with microdialysis capability. We modified a rotating cage by adding operant behavior testing components to the side of the bowl-shaped cage. A modular on-board controlle"],"journal":["Journal of neuroscience methods"],"pubmed_title":["A rotating operant chamber for use with microdialysis."],"pmcid":["PMC6717681"],"funding_grant_id":["R01 MH104386"],"pubmed_authors":["Degreef B","Weber SG","Jaquins-Gerstl A","Ngo KT"],"additional_accession":[]},"is_claimable":false,"name":"A rotating operant chamber for use with microdialysis.","description":"<h4>Background</h4>Recently, the time resolution of microdialysis followed by a chemical separation for quantitative analysis has improved. The advent of faster microdialysis measurements promises to aid in behavioral research on awake animals. However, microdialysis with awake animals generally employs a fluidic commutator (swivel). The swivel's volume is inimical to the time resolution of the measurements.<h4>New method</h4>Animals can be housed in rotating cages so that the swivel is not required, but rotating operant chambers are not available. Here we describe the design and construction of a rotating operant chamber with microdialysis capability. We modified a rotating cage by adding operant behavior testing components to the side of the bowl-shaped cage. A modular on-board controlle","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Oct","modification":"2025-05-29T19:11:15.51Z","creation":"2020-10-08T07:26:11Z"},"accession":"S-EPMC6717681","cross_references":{"pubmed":["31377176"],"doi":["10.1016/j.jneumeth.2019.108387"]}}