{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["von Versen-Hoynck F"],"funding":["NICHD NIH HHS","Deutsche Forschungsgemeinschaft","NIH HHS"],"pagination":["412-419"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6728556"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(3)"],"pubmed_abstract":["<h4>Objective</h4>To investigate how the mode of conception affects maternal relaxin, creatinine, and electrolyte concentrations.<h4>Background</h4>Pregnancies achieved by fertility treatment often begin in a nonphysiologic endocrine milieu with no corpus luteum (CL) or with many corpora lutea. The CL produces not only estradiol and progesterone but is also the sole source of relaxin in early pregnancy, a hormone that may contribute to maternal systemic and renal vasodilation. There is limited data about maternal physiology in early pregnancy during fertility treatment, and studies have rarely considered the potential effect of the absence of the CL. To begin to address this gap in knowledge, we sought to investigate how the mode of conception affects maternal relaxin, creatinine, and elec"],"journal":["Reproductive sciences (Thousand Oaks, Calif.)"],"pubmed_title":["Effect of Mode of Conception on Maternal Serum Relaxin, Creatinine, and Sodium Concentrations in an Infertile Population."],"pmcid":["PMC6728556"],"funding_grant_id":["VE490/8-1","P01 HD 065647-01A1","P01 HD065647"],"pubmed_authors":["Liu J","Chi YY","Conrad KP","Keller-Woods M","Baker VL","von Versen-Hoynck F","Strauch NK"],"additional_accession":[]},"is_claimable":false,"name":"Effect of Mode of Conception on Maternal Serum Relaxin, Creatinine, and Sodium Concentrations in an Infertile Population.","description":"<h4>Objective</h4>To investigate how the mode of conception affects maternal relaxin, creatinine, and electrolyte concentrations.<h4>Background</h4>Pregnancies achieved by fertility treatment often begin in a nonphysiologic endocrine milieu with no corpus luteum (CL) or with many corpora lutea. The CL produces not only estradiol and progesterone but is also the sole source of relaxin in early pregnancy, a hormone that may contribute to maternal systemic and renal vasodilation. There is limited data about maternal physiology in early pregnancy during fertility treatment, and studies have rarely considered the potential effect of the absence of the CL. To begin to address this gap in knowledge, we sought to investigate how the mode of conception affects maternal relaxin, creatinine, and elec","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Mar","modification":"2025-04-26T01:03:41.662Z","creation":"2021-02-21T12:14:57Z"},"accession":"S-EPMC6728556","cross_references":{"pubmed":["29862889"],"doi":["10.1177/1933719118776792"]}}