biostudies-literatureUnknown45(5)Goze TThe "Praecox Feeling" (PF) is a classical concept referring to a characteristic feeling of bizarreness experienced by a psychiatrist while encountering a person with schizophrenia. Although the PF used to be considered a core symptom of the schizophrenia spectrum, it fell into disuse since the spread of operationalized diagnostic methods (Diagnostic and Statistical Manual of Mental Disorders/International Classification of Diseases systems). In contemporary research on schizophrenia, it remains largely unaddressed. This critical review investigates the evolution of the PF in historical and contemporary literature and presents an exhaustive overview of empirical evidence on its prevalence in clinical decision making, its reliability and validity. The review demonstrates that the PF is a reaSchizophrenia bulletin966-970https://www.ebi.ac.uk/biostudies/studies/S-EPMC6737542biostudies-literatureReassessing "Praecox Feeling" in Diagnostic Decision Making in Schizophrenia: A Critical Review.PMC6737542Naudin JCermolacce MMoskalewicz MGoze TSchwartz MAMicoulaud-Franchi JAfalseReassessing "Praecox Feeling" in Diagnostic Decision Making in Schizophrenia: A Critical Review.The "Praecox Feeling" (PF) is a classical concept referring to a characteristic feeling of bizarreness experienced by a psychiatrist while encountering a person with schizophrenia. Although the PF used to be considered a core symptom of the schizophrenia spectrum, it fell into disuse since the spread of operationalized diagnostic methods (Diagnostic and Statistical Manual of Mental Disorders/International Classification of Diseases systems). In contemporary research on schizophrenia, it remains largely unaddressed. This critical review investigates the evolution of the PF in historical and contemporary literature and presents an exhaustive overview of empirical evidence on its prevalence in clinical decision making, its reliability and validity. The review demonstrates that the PF is a rea2019-01-01T00:00:00Z2019 Sep2025-05-18T11:50:27.772Z2025-05-18T11:50:27.772ZS-EPMC67375423047634010.1093/schbul/sby172