{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mondo SJ"],"funding":["Universidad de los Andes","Office of Science"],"pagination":["229"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6757388"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12"],"pubmed_abstract":["<h4>Background</h4>Particular species of the genus <i>Coniochaeta</i> (Sordariomycetes) exhibit great potential for bioabatement of furanic compounds and have been identified as an underexplored source of novel lignocellulolytic enzymes, especially <i>Coniochaeta ligniaria</i>. However, there is a lack of information about their genomic features and metabolic capabilities. Here, we report the first in-depth genome/transcriptome survey of a <i>Coniochaeta</i> species (strain 2T2.1).<h4>Results</h4>The genome of <i>Coniochaeta</i> sp. strain 2T2.1 has a size of 74.53 Mbp and contains 24,735 protein-encoding genes. Interestingly, we detected a genome expansion event, resulting ~ 98% of the assembly being duplicated with 91.9% average nucleotide identity between the duplicated regions. The lac"],"journal":["Biotechnology for biofuels"],"pubmed_title":["Genome expansion by allopolyploidization in the fungal strain <i>Coniochaeta</i> 2T2.1 and its exceptional lignocellulolytic machinery."],"pmcid":["PMC6757388"],"funding_grant_id":["PR.3.2018.5287","DE-AC02-05CH11231"],"pubmed_authors":["Yan M","Grigoriev IV","LaButti K","Hector RE","Jimenez DJ","Nichols NN","Mondo SJ","Barry K","van Elsas JD","Lipzen A"],"additional_accession":[]},"is_claimable":false,"name":"Genome expansion by allopolyploidization in the fungal strain <i>Coniochaeta</i> 2T2.1 and its exceptional lignocellulolytic machinery.","description":"<h4>Background</h4>Particular species of the genus <i>Coniochaeta</i> (Sordariomycetes) exhibit great potential for bioabatement of furanic compounds and have been identified as an underexplored source of novel lignocellulolytic enzymes, especially <i>Coniochaeta ligniaria</i>. However, there is a lack of information about their genomic features and metabolic capabilities. Here, we report the first in-depth genome/transcriptome survey of a <i>Coniochaeta</i> species (strain 2T2.1).<h4>Results</h4>The genome of <i>Coniochaeta</i> sp. strain 2T2.1 has a size of 74.53 Mbp and contains 24,735 protein-encoding genes. Interestingly, we detected a genome expansion event, resulting ~ 98% of the assembly being duplicated with 91.9% average nucleotide identity between the duplicated regions. The lac","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2025-04-04T22:12:00.011Z","creation":"2019-10-11T07:10:18Z"},"accession":"S-EPMC6757388","cross_references":{"pubmed":["31572496"],"doi":["10.1186/s13068-019-1569-6"]}}