biostudies-literatureMondo SJUniversidad de los AndesOffice of Science229https://www.ebi.ac.uk/biostudies/studies/S-EPMC6757388biostudies-literatureUnknown12<h4>Background</h4>Particular species of the genus <i>Coniochaeta</i> (Sordariomycetes) exhibit great potential for bioabatement of furanic compounds and have been identified as an underexplored source of novel lignocellulolytic enzymes, especially <i>Coniochaeta ligniaria</i>. However, there is a lack of information about their genomic features and metabolic capabilities. Here, we report the first in-depth genome/transcriptome survey of a <i>Coniochaeta</i> species (strain 2T2.1).<h4>Results</h4>The genome of <i>Coniochaeta</i> sp. strain 2T2.1 has a size of 74.53 Mbp and contains 24,735 protein-encoding genes. Interestingly, we detected a genome expansion event, resulting ~ 98% of the assembly being duplicated with 91.9% average nucleotide identity between the duplicated regions. The lacBiotechnology for biofuelsGenome expansion by allopolyploidization in the fungal strain <i>Coniochaeta</i> 2T2.1 and its exceptional lignocellulolytic machinery.PMC6757388PR.3.2018.5287DE-AC02-05CH11231Yan MGrigoriev IVLaButti KHector REJimenez DJNichols NNMondo SJBarry Kvan Elsas JDLipzen AfalseGenome expansion by allopolyploidization in the fungal strain <i>Coniochaeta</i> 2T2.1 and its exceptional lignocellulolytic machinery.<h4>Background</h4>Particular species of the genus <i>Coniochaeta</i> (Sordariomycetes) exhibit great potential for bioabatement of furanic compounds and have been identified as an underexplored source of novel lignocellulolytic enzymes, especially <i>Coniochaeta ligniaria</i>. However, there is a lack of information about their genomic features and metabolic capabilities. Here, we report the first in-depth genome/transcriptome survey of a <i>Coniochaeta</i> species (strain 2T2.1).<h4>Results</h4>The genome of <i>Coniochaeta</i> sp. strain 2T2.1 has a size of 74.53 Mbp and contains 24,735 protein-encoding genes. Interestingly, we detected a genome expansion event, resulting ~ 98% of the assembly being duplicated with 91.9% average nucleotide identity between the duplicated regions. The lac2019-01-01T00:00:00Z20192025-04-04T22:12:00.011Z2019-10-11T07:10:18ZS-EPMC67573883157249610.1186/s13068-019-1569-6