biostudies-literatureAugustin AUEuropean Union (Horizon 2020)11620-11624https://www.ebi.ac.uk/biostudies/studies/S-EPMC6771889biostudies-literatureUnknown25(50)A 1,3-aminothiolation was realized by reacting 2-substituted cyclopropane 1,1-dicarboxylates with sulfonamides and N-(arylthio)succinimides. Under Sn(OTf)₂ catalysis the transformation proceeded smoothly to the corresponding ring-opened products bearing the sulfonamide in the 1-position next to the donor and the arylthio residue in the 3-position next to the acceptor. The procedure was extended to the corresponding selenium analogues by employing N-(phenylseleno)succinimides as an electrophilic selenium source.Chemistry (Weinheim an der Bergstrasse, Germany)Ring-Opening 1,3-Aminochalcogenation of Donor-Acceptor Cyclopropanes: A Three-Component Approach.PMC6771889GAINBYSTRAINAugustin AUJones PGWerz DBfalseRing-Opening 1,3-Aminochalcogenation of Donor-Acceptor Cyclopropanes: A Three-Component Approach.A 1,3-aminothiolation was realized by reacting 2-substituted cyclopropane 1,1-dicarboxylates with sulfonamides and N-(arylthio)succinimides. Under Sn(OTf)₂ catalysis the transformation proceeded smoothly to the corresponding ring-opened products bearing the sulfonamide in the 1-position next to the donor and the arylthio residue in the 3-position next to the acceptor. The procedure was extended to the corresponding selenium analogues by employing N-(phenylseleno)succinimides as an electrophilic selenium source.2019-01-01T00:00:00Z2019 Sep2025-04-04T08:26:30.275Z2019-10-16T07:05:46ZS-EPMC67718893128200110.1002/chem.201902160