{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Palma A"],"funding":["Associazione Italiana per la Ricerca sul Cancro","European Research Council"],"pagination":["1216"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6776608"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10"],"pubmed_abstract":["Muscle regeneration is a complex process governed by the interplay between several muscle-resident mononuclear cell populations. Following acute or chronic damage these cell populations are activated, communicate via cell-cell interactions and/or paracrine signals, influencing fate decisions via the activation or repression of internal signaling cascades. These are highly dynamic processes, occurring with distinct temporal and spatial kinetics. The main challenge toward a system level description of the muscle regeneration process is the integration of this plethora of inter- and intra-cellular interactions. We integrated the information on muscle regeneration in a web portal. The scientific content annotated in this portal is organized into two information layers representing relationship"],"journal":["Frontiers in physiology"],"pubmed_title":["Myo-REG: A Portal for Signaling Interactions in Muscle Regeneration."],"pmcid":["PMC6776608"],"funding_grant_id":["322749"],"pubmed_authors":["Giuliani G","Cesareni G","Ferrentino F","Fuoco C","Sacco F","Palma A","Zuccotti A","Iannuccelli M","Reggio A","Licata L","Vumbaca S","Castagnoli L","Paoluzi S","Micarelli E","Perfetto L","Petrilli LL","Gargioli C","Cerquone Perpetuini A","Rosina M"],"additional_accession":[]},"is_claimable":false,"name":"Myo-REG: A Portal for Signaling Interactions in Muscle Regeneration.","description":"Muscle regeneration is a complex process governed by the interplay between several muscle-resident mononuclear cell populations. Following acute or chronic damage these cell populations are activated, communicate via cell-cell interactions and/or paracrine signals, influencing fate decisions via the activation or repression of internal signaling cascades. These are highly dynamic processes, occurring with distinct temporal and spatial kinetics. The main challenge toward a system level description of the muscle regeneration process is the integration of this plethora of inter- and intra-cellular interactions. We integrated the information on muscle regeneration in a web portal. The scientific content annotated in this portal is organized into two information layers representing relationship","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2025-04-04T08:29:54.494Z","creation":"2019-10-18T07:02:58Z"},"accession":"S-EPMC6776608","cross_references":{"pubmed":["31611808"],"doi":["10.3389/fphys.2019.01216"]}}