biostudies-literatureKopczynska MFiona Elizabeth Agnew Trust: FeaturesE1337https://www.ebi.ac.uk/biostudies/studies/S-EPMC6780948biostudies-literatureUnknown8(9)Recent description of the microbiology of sepsis on the wards or information on the real-life antibiotic choices used in sepsis is lacking. There is growing concern of the indiscriminate use of antibiotics and omission of microbiological investigations in the management of septic patients. We performed a secondary analysis of three annual 24-h point-prevalence studies on the general wards across all Welsh acute hospitals in years 2016-2018. Data were collected on patient demographics, as well as radiological, laboratory and microbiological data within 48-h of the study. We screened 19,453 patients over the three 24 h study periods and recruited 1252 patients who fulfilled the entry criteria. 775 (64.9%) patients were treated with intravenous antibiotics. Only in 33.65% (421/1252) of all reJournal of clinical medicineReal World Patterns of Antimicrobial Use and Microbiology Investigations in Patients with Sepsis outside the Critical Care Unit: Secondary Analysis of Three Nation-Wide Point Prevalence Studies.PMC6780948Award 2015Award 2016Szakmany TChandy TAmjad YGanesananthan SUnwin HForrester ARoss RKurani ASharma AZeicu CKopczynska MUnadkat VWaller APenney HAng EOwen AAsim UTan ZXWellington JLynch JCleaver SNicholas JSharif BGilbert CHussain FInns JMurphy ESmith JKulikouskaya SPayne BGrother TDoyle NMcNulty PfalseReal World Patterns of Antimicrobial Use and Microbiology Investigations in Patients with Sepsis outside the Critical Care Unit: Secondary Analysis of Three Nation-Wide Point Prevalence Studies.Recent description of the microbiology of sepsis on the wards or information on the real-life antibiotic choices used in sepsis is lacking. There is growing concern of the indiscriminate use of antibiotics and omission of microbiological investigations in the management of septic patients. We performed a secondary analysis of three annual 24-h point-prevalence studies on the general wards across all Welsh acute hospitals in years 2016-2018. Data were collected on patient demographics, as well as radiological, laboratory and microbiological data within 48-h of the study. We screened 19,453 patients over the three 24 h study periods and recruited 1252 patients who fulfilled the entry criteria. 775 (64.9%) patients were treated with intravenous antibiotics. Only in 33.65% (421/1252) of all re2019-01-01T00:00:00Z2019 Aug2025-04-20T00:23:47.243Z2019-11-07T08:04:28ZS-EPMC67809483147056910.3390/jcm8091337