{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Black DM"],"funding":["Welch Foundation"],"pagination":["E1303"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6781097"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(9)"],"pubmed_abstract":["Gold clusters protected by 3-MBA ligands (MBA = mercaptobenzoic acid, -SPhCO2H) have attracted recent interest due to their unusual structures and their advantageous ligand-exchange and bioconjugation properties. Azubel et al. first determined the core structure of an Au68-complex, which was estimated to have 32 ligands (3-MBA groups). To explain the exceptional structure-composition and reaction properties of this complex, and its larger homologs, Tero et al. proposed a \"dynamic stabilization\" via carboxyl O-H--Au interactions. Herein, we report the first results of an integrated liquid chromatography/mass spectrometer (LC/MS) analysis of unfractionated samples of gold/3-MBA clusters, spanning a narrow size range 13.4 to 18.1 kDa. Using high-throughput procedures adapted from bio-macromol"],"journal":["Nanomaterials (Basel, Switzerland)"],"pubmed_title":["New Evidence of the Bidentate Binding Mode in 3-MBA Protected Gold Clusters: Analysis of Aqueous 13-18 kDa Gold-Thiolate Clusters by HPLC-ESI-MS Reveals Special Compositions Aun(3-MBA)p, (n = 48-67, p = 26-30)."],"pmcid":["PMC6781097"],"funding_grant_id":["AX-1857"],"pubmed_authors":["Black DM","Placencia-Villa G","Hoque MM","Whetten RL"],"additional_accession":[]},"is_claimable":false,"name":"New Evidence of the Bidentate Binding Mode in 3-MBA Protected Gold Clusters: Analysis of Aqueous 13-18 kDa Gold-Thiolate Clusters by HPLC-ESI-MS Reveals Special Compositions Aun(3-MBA)p, (n = 48-67, p = 26-30).","description":"Gold clusters protected by 3-MBA ligands (MBA = mercaptobenzoic acid, -SPhCO2H) have attracted recent interest due to their unusual structures and their advantageous ligand-exchange and bioconjugation properties. Azubel et al. first determined the core structure of an Au68-complex, which was estimated to have 32 ligands (3-MBA groups). To explain the exceptional structure-composition and reaction properties of this complex, and its larger homologs, Tero et al. proposed a \"dynamic stabilization\" via carboxyl O-H--Au interactions. Herein, we report the first results of an integrated liquid chromatography/mass spectrometer (LC/MS) analysis of unfractionated samples of gold/3-MBA clusters, spanning a narrow size range 13.4 to 18.1 kDa. Using high-throughput procedures adapted from bio-macromol","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Sep","modification":"2025-04-20T00:25:25.217Z","creation":"2019-11-07T08:04:30Z"},"accession":"S-EPMC6781097","cross_references":{"pubmed":["31514483"],"doi":["10.3390/nano9091303"]}}