{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(9)"],"submitter":["Ikehara T"],"pubmed_abstract":["Microcystins (MCs) are a group of cyclic heptapeptide hepatotoxins produced by <i>Microcystis</i> and several other genera of cyanobacteria. Many structural variants have been characterized using various methods such as liquid chromatography-mass spectrometry (LC-MS) analysis, enzyme-linked immunosorbent assay (ELISA) and protein phosphatase 2A (PP2A) inhibition assay. The representative MC, MC-LR, and related cyanobacterial toxins strongly inhibit PP2A activity and can therefore be assayed by measuring the extent of PP2A inhibition. However, these methods require reference toxin standards for the quantification and identification of known MCs. To obtain various MC-producing cyanobacterial strains, we surveyed and collected MC-producing cyanobacteria from environmental sources of water in "],"journal":["Toxins"],"pagination":["E521"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6784158"],"repository":["biostudies-literature"],"pubmed_title":["First Report of <i>Microcystis</i> Strains Producing MC-FR and -WR Toxins in Japan."],"pmcid":["PMC6784158"],"pubmed_authors":["Kuniyoshi K","Ikehara T","Tanabe Y","Yamaguchi H","Yoshimoto M","Yasumoto-Hirose M","Oshiro N","Sano T","Nakashima S"],"additional_accession":[]},"is_claimable":false,"name":"First Report of <i>Microcystis</i> Strains Producing MC-FR and -WR Toxins in Japan.","description":"Microcystins (MCs) are a group of cyclic heptapeptide hepatotoxins produced by <i>Microcystis</i> and several other genera of cyanobacteria. Many structural variants have been characterized using various methods such as liquid chromatography-mass spectrometry (LC-MS) analysis, enzyme-linked immunosorbent assay (ELISA) and protein phosphatase 2A (PP2A) inhibition assay. The representative MC, MC-LR, and related cyanobacterial toxins strongly inhibit PP2A activity and can therefore be assayed by measuring the extent of PP2A inhibition. However, these methods require reference toxin standards for the quantification and identification of known MCs. To obtain various MC-producing cyanobacterial strains, we surveyed and collected MC-producing cyanobacteria from environmental sources of water in ","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Sep","modification":"2026-04-07T13:52:07.132Z","creation":"2019-10-30T08:19:02Z"},"accession":"S-EPMC6784158","cross_references":{"pubmed":["31505765"],"doi":["10.3390/toxins11090521"]}}