{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Whitaker J"],"funding":["British Heart Foundation","Medical Research Council","NHLBI NIH HHS","National Institute for Health Research (NIHR)","Health Innovation Challenge Fund","Wellcome Trust","Engineering and Physical Sciences Research Council"],"pagination":["62"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6785908"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21(1)"],"pubmed_abstract":["Background
Ex-vivo cardiovascular magnetic resonance (CMR) imaging has played an important role in the validation of in-vivo CMR characterization of pathological processes. However, comparison between in-vivo and ex-vivo imaging remains challenging due to shape changes occurring between the two states, which may be non-uniform across the diseased heart. A novel two-step process to facilitate registration between ex-vivo and in-vivo CMR was developed and evaluated in a porcine model of chronic myocardial infarction (MI).Methods
Seven weeks after ischemia-reperfusion MI, 12 swine underwent in-vivo CMR imaging with late gadolinium enhancement followed by ex-vivo CMR 1 week later. Five animals comprised the control group, in which ex-vivo imaging was undertaken without any supp"],"journal":["Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance"],"pubmed_title":["Improved co-registration of ex-vivo and in-vivo cardiovascular magnetic resonance images using heart-specific flexible 3D printed acrylic scaffold combined with non-rigid registration."],"pmcid":["PMC6785908"],"funding_grant_id":["FS/18/27/33543","CL-2015-17-502","ACF-2013-17-008","EP/R010935/1","EP/P01268X/1","HICF-R10-698","MR/N001877/1","R01 HL129185","WT 203148/Z/16/Z"],"pubmed_authors":["Chubb H","Niederer S","Razavi R","O'Neill M","O'Neill L","Anter E","Roujol S","Rhode K","Puyol-Anton E","King A","Byrne N","Tschabrunn C","Mukherjee RK","Neji R","Bishop MJ","Connolly A","Razeghi O","Whitaker J","Nezafat R","Williams SE"],"additional_accession":[]},"is_claimable":false,"name":"Improved co-registration of ex-vivo and in-vivo cardiovascular magnetic resonance images using heart-specific flexible 3D printed acrylic scaffold combined with non-rigid registration.","description":"Background
Ex-vivo cardiovascular magnetic resonance (CMR) imaging has played an important role in the validation of in-vivo CMR characterization of pathological processes. However, comparison between in-vivo and ex-vivo imaging remains challenging due to shape changes occurring between the two states, which may be non-uniform across the diseased heart. A novel two-step process to facilitate registration between ex-vivo and in-vivo CMR was developed and evaluated in a porcine model of chronic myocardial infarction (MI).Methods
Seven weeks after ischemia-reperfusion MI, 12 swine underwent in-vivo CMR imaging with late gadolinium enhancement followed by ex-vivo CMR 1 week later. Five animals comprised the control group, in which ex-vivo imaging was undertaken without any supp","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Oct","modification":"2026-05-07T12:38:54.263Z","creation":"2025-05-29T20:17:09.946Z"},"accession":"S-EPMC6785908","cross_references":{"pubmed":["31597563"],"doi":["10.1186/s12968-019-0574-z"]}}