biostudies-literatureDonnelly SRIntramural NIH HHSNovo Nordisk FoundationInnovation Fund DenmarkEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNICHD NIH HHSDanish Diabetes AcademyInnovationsfonden'Centre for Fetal Programming', The Health FoundationEuropean CommissionMarch of Dimes Birth Defects FoundationEuropean UnionHeart FoundationHjerteforeningenNovo Nordisk FondenNIGMS NIH HHS895-905https://www.ebi.ac.uk/biostudies/studies/S-EPMC6791726biostudies-literatureUnknown11(11)<h4>Background</h4>Women with gestational diabetes mellitus (GDM) may be at an increased risk of liver complications because chronic hyperglycemia is a risk factor for liver fat accumulation and potential liver dysfunction. Large prospective studies examining liver fat accumulation following a GDM pregnancy are lacking.<h4>Methods</h4>The Diabetes & Women's Health Study (2012-2014) examined the association between GDM and subsequent fatty liver scores among 607 women with and 619 women without GDM in the Danish National Birth Cohort. Nine to 16 years postpartum, a clinical examination was performed, with measurement of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyl transferase, from which fatty liver scoring indices were calculated to assess liver fat scorJournal of diabetesProspective study of gestational diabetes and fatty liver scores 9 to 16 years after pregnancy.PMC6791726P20 GM109036FP7‐28934696‐2‐4‐83‐2245009‐6712496-2-4-83-2245011-115923HHSN275201300026IFP7-28934611/263-966-FY-96-0240HSN275201100002I11‐115923ZIA HD008916HHSN275201000020CHHSN275201500003C09-671246-FY00-4076-FY97-05536-FY97-0521Wu JLey SHHu FBGore-Langton REOlsen SFDonnelly SRGrunnet LGTsai MYLi MBjerregaard AAFrancis ECMills JLChavarro JEVaag ARawal SThuesen ACBHinkle SNZhang CDamm PfalseProspective study of gestational diabetes and fatty liver scores 9 to 16 years after pregnancy.<h4>Background</h4>Women with gestational diabetes mellitus (GDM) may be at an increased risk of liver complications because chronic hyperglycemia is a risk factor for liver fat accumulation and potential liver dysfunction. Large prospective studies examining liver fat accumulation following a GDM pregnancy are lacking.<h4>Methods</h4>The Diabetes & Women's Health Study (2012-2014) examined the association between GDM and subsequent fatty liver scores among 607 women with and 619 women without GDM in the Danish National Birth Cohort. Nine to 16 years postpartum, a clinical examination was performed, with measurement of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyl transferase, from which fatty liver scoring indices were calculated to assess liver fat scor2019-01-01T00:00:00Z2019 Nov2026-04-14T15:16:44.28Z2020-11-03T08:05:32ZS-EPMC67917263100191510.1111/1753-0407.12934