{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(1)"],"submitter":["Li J"],"pubmed_abstract":["<h4>Background</h4>The study aims at scientifically investigating the genetic effect of four polymorphisms (rs7975232, rs1544410, rs2228570, and rs731236) within the human Vitamin D Receptor (VDR) gene on the odds of psoriasis through an updated meta-analysis.<h4>Methods</h4>We searched eight databases and screened the studies for pooling. Finally, a total of eighteen eligible case-control studies were included. BH (Benjamini & Hochberg) adjusted P-values of association (P<sub>association</sub>) and odd ratios (ORs) with the corresponding 95% confidence intervals (CIs) were calculated under the allele, homozygote, heterozygote, dominant, recessive, and carrier models.<h4>Results</h4>Compared with the negative controls, no statistically significant difference in the odds of psoriasis was de"],"journal":["BMC medical genetics"],"pagination":["161"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6796361"],"repository":["biostudies-literature"],"pubmed_title":["Pooling analysis regarding the impact of human vitamin D receptor variants on the odds of psoriasis."],"pmcid":["PMC6796361"],"pubmed_authors":["Sun L","Yan M","Li J","Sun J"],"additional_accession":[]},"is_claimable":false,"name":"Pooling analysis regarding the impact of human vitamin D receptor variants on the odds of psoriasis.","description":"<h4>Background</h4>The study aims at scientifically investigating the genetic effect of four polymorphisms (rs7975232, rs1544410, rs2228570, and rs731236) within the human Vitamin D Receptor (VDR) gene on the odds of psoriasis through an updated meta-analysis.<h4>Methods</h4>We searched eight databases and screened the studies for pooling. Finally, a total of eighteen eligible case-control studies were included. BH (Benjamini & Hochberg) adjusted P-values of association (P<sub>association</sub>) and odd ratios (ORs) with the corresponding 95% confidence intervals (CIs) were calculated under the allele, homozygote, heterozygote, dominant, recessive, and carrier models.<h4>Results</h4>Compared with the negative controls, no statistically significant difference in the odds of psoriasis was de","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Oct","modification":"2026-05-03T16:34:42.661Z","creation":"2019-11-05T08:06:58Z"},"accession":"S-EPMC6796361","cross_references":{"pubmed":["31623568"],"doi":["10.1186/s12881-019-0896-6"]}}