{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(10)"],"submitter":["Chong P"],"pubmed_abstract":["The haploid fungus Pseudocercospora fijiensis causes black Sigatoka in banana and is chiefly controlled by extensive fungicide applications, threatening occupational health and the environment. The 14α-Demethylase Inhibitors (DMIs) are important disease control fungicides, but they lose sensitivity in a rather gradual fashion, suggesting an underlying polygenic genetic mechanism. In spite of this, evidence found thus far suggests that P. fijiensis cyp51 gene mutations are the main responsible factor for sensitivity loss in the field. To better understand the mechanisms involved in DMI resistance, in this study we constructed a genetic map using DArTseq markers on two F1 populations generated by crossing two different DMI resistant strains with a sensitive strain. Analysis of the inheritanc"],"journal":["PloS one"],"pagination":["e0223858"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6797121"],"repository":["biostudies-literature"],"pubmed_title":["Pfcyp51 exclusively determines reduced sensitivity to 14α-demethylase inhibitor fungicides in the banana black Sigatoka pathogen Pseudocercospora fijiensis."],"pmcid":["PMC6797121"],"pubmed_authors":["Kema GHJ","Arango Isaza RE","Chong P","Schouten HJ","Vichou AE","Meijer HJG"],"additional_accession":[]},"is_claimable":false,"name":"Pfcyp51 exclusively determines reduced sensitivity to 14α-demethylase inhibitor fungicides in the banana black Sigatoka pathogen Pseudocercospora fijiensis.","description":"The haploid fungus Pseudocercospora fijiensis causes black Sigatoka in banana and is chiefly controlled by extensive fungicide applications, threatening occupational health and the environment. The 14α-Demethylase Inhibitors (DMIs) are important disease control fungicides, but they lose sensitivity in a rather gradual fashion, suggesting an underlying polygenic genetic mechanism. In spite of this, evidence found thus far suggests that P. fijiensis cyp51 gene mutations are the main responsible factor for sensitivity loss in the field. To better understand the mechanisms involved in DMI resistance, in this study we constructed a genetic map using DArTseq markers on two F1 populations generated by crossing two different DMI resistant strains with a sensitive strain. Analysis of the inheritanc","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2026-05-04T14:32:55.011Z","creation":"2019-11-05T08:07:30Z"},"accession":"S-EPMC6797121","cross_references":{"pubmed":["31622393"],"doi":["10.1371/journal.pone.0223858"]}}