{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Halstead FD"],"funding":["National Institute for Health Research (NIHR)"],"pagination":["e01346-19"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6803304"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["85(21)"],"pubmed_abstract":["Light-emitting diodes (LEDs) demonstrate therapeutic effects for a range of biomedical applications, including photodisinfection. Bands of specific wavelengths (centered at 405 nm) are reported to be the most antimicrobial; however, there remains no consensus on the most effective irradiation parameters for optimal photodisinfection. The aim of this study was to assess decontamination efficiency by direct photodisinfection of monomicrobial biofilms using a violet-blue light (VBL) single-wavelength array (SWA) and multiwavelength array (MWA). Mature biofilms of nosocomial bacteria (Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus) were grown on 96-well polypropylene PCR plates. The biofilms were then exposed to VBL for 2,700 s (SWA) and 1,170 s (M"],"journal":["Applied and environmental microbiology"],"pubmed_title":["Violet-Blue Light Arrays at 405 Nanometers Exert Enhanced Antimicrobial Activity for Photodisinfection of Monomicrobial Nosocomial Biofilms."],"pmcid":["PMC6803304"],"funding_grant_id":["Surgical Reconstruction and Microbiology Research Centre"],"pubmed_authors":["Marley N","Palin WM","Halstead FD","Cooper PR","Oppenheim B","Brock K","Hadis MA","Milward MR"],"additional_accession":[]},"is_claimable":false,"name":"Violet-Blue Light Arrays at 405 Nanometers Exert Enhanced Antimicrobial Activity for Photodisinfection of Monomicrobial Nosocomial Biofilms.","description":"Light-emitting diodes (LEDs) demonstrate therapeutic effects for a range of biomedical applications, including photodisinfection. Bands of specific wavelengths (centered at 405 nm) are reported to be the most antimicrobial; however, there remains no consensus on the most effective irradiation parameters for optimal photodisinfection. The aim of this study was to assess decontamination efficiency by direct photodisinfection of monomicrobial biofilms using a violet-blue light (VBL) single-wavelength array (SWA) and multiwavelength array (MWA). Mature biofilms of nosocomial bacteria (Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus) were grown on 96-well polypropylene PCR plates. The biofilms were then exposed to VBL for 2,700 s (SWA) and 1,170 s (M","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Nov","modification":"2025-04-19T03:13:39.926Z","creation":"2019-11-07T08:05:22Z"},"accession":"S-EPMC6803304","cross_references":{"pubmed":["31444205"],"doi":["10.1128/AEM.01346-19"]}}