{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ji Y"],"funding":["National Natural Science Foundation of China"],"pagination":["E3568"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6804229"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(19)"],"pubmed_abstract":["Hypericum stellatum, a species endemic to China, is used to treat hepatitis by several ethnic groups in Guizhou Province. This research was inspired by the traditional medicinal usage of H. stellatum, and aims to explore the phytochemistry and bioactivity of H. stellatum to explain why local people in Guizhou widely apply H. stellatum for liver protection. In this study, two new prenylated xanthones, hypxanthones A (8) and B (9), together with seven known compounds, were isolated from the aerial parts of the plant. Spectroscopic data as well as experimental and calculated ECD spectra were used to establish the structures of these compounds. Six xanthones isolated in this study, together with four xanthones previously isolated from H. stellatum, were evaluated for their growth-inhibitory ac"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Cytotoxic Xanthones from Hypericum stellatum, an Ethnomedicine in Southwest China."],"pmcid":["PMC6804229"],"funding_grant_id":["31870316 & 31761143001"],"pubmed_authors":["Li X","Yuan C","Negrin A","Kennelly EJ","Ji Y","Zhang C","Zhang R","Long C"],"additional_accession":[]},"is_claimable":false,"name":"Cytotoxic Xanthones from Hypericum stellatum, an Ethnomedicine in Southwest China.","description":"Hypericum stellatum, a species endemic to China, is used to treat hepatitis by several ethnic groups in Guizhou Province. This research was inspired by the traditional medicinal usage of H. stellatum, and aims to explore the phytochemistry and bioactivity of H. stellatum to explain why local people in Guizhou widely apply H. stellatum for liver protection. In this study, two new prenylated xanthones, hypxanthones A (8) and B (9), together with seven known compounds, were isolated from the aerial parts of the plant. Spectroscopic data as well as experimental and calculated ECD spectra were used to establish the structures of these compounds. Six xanthones isolated in this study, together with four xanthones previously isolated from H. stellatum, were evaluated for their growth-inhibitory ac","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Oct","modification":"2025-04-20T00:24:53.774Z","creation":"2020-05-21T19:00:42Z"},"accession":"S-EPMC6804229","cross_references":{"pubmed":["31581734"],"doi":["10.3390/molecules24193568"]}}