biostudies-literatureUnknown7(11)Vanella GBackground and aims A split-dose regimen for colonoscopy is recommended by international guidelines, but its adoption is still suboptimal. Our aim was to assess whether a Plan-Do-Study-Act approach (PDSA), a scientific method promoting quality improvement, would be able to improve adherence to a split-dose regimen, and to identify factors influencing its adoption. Methods This study consisted of three phases: Cycle 1: a cross-sectional assessment of split-dose adherence in consecutive outpatients/inpatients undergoing colonoscopies in 74 Italian centers; Educational intervention: regional meetings with literature review, analysis of Cycle 1 data, and discussion on corrective measures; local diffusion of educational material and tools for improvement; Cycle 2: reassessment oEndoscopy international openE1457-E1467https://www.ebi.ac.uk/biostudies/studies/S-EPMC6805191biostudies-literatureIMPlementing split Regimen OVEr Single dose using a Plan-Do-Study-Act approach (IMPROVES study).PMC6805191De Bellis MTarantino OGrasso ELaterza FDi Giulio EGiardini MHassan CVanella GfalseIMPlementing split Regimen OVEr Single dose using a Plan-Do-Study-Act approach (IMPROVES study).Background and aims A split-dose regimen for colonoscopy is recommended by international guidelines, but its adoption is still suboptimal. Our aim was to assess whether a Plan-Do-Study-Act approach (PDSA), a scientific method promoting quality improvement, would be able to improve adherence to a split-dose regimen, and to identify factors influencing its adoption. Methods This study consisted of three phases: Cycle 1: a cross-sectional assessment of split-dose adherence in consecutive outpatients/inpatients undergoing colonoscopies in 74 Italian centers; Educational intervention: regional meetings with literature review, analysis of Cycle 1 data, and discussion on corrective measures; local diffusion of educational material and tools for improvement; Cycle 2: reassessment o2019-01-01T00:00:00Z2019 Nov2026-04-15T23:17:48.513Z2019-11-07T08:05:26ZS-EPMC68051913167361810.1055/a-0996-8118