biostudies-literatureUnknown24(20)Liu ZA practical synthesis of the very rare sugar d-idose and the stable building blocks for d-idose, d-iduronic, and d-idonic acids from ido-heptonic acid requires only isopropylidene protection, Shing silica gel-supported periodate cleavage of the C6-C7 bond of the heptonic acid, and selective reduction of C1 and/or C6. d-Idose is the most unstable of all the aldohexoses and a stable precursor which be stored and then converted under very mild conditions into d-idose is easily prepared.Molecules (Basel, Switzerland)E3758https://www.ebi.ac.uk/biostudies/studies/S-EPMC6832733biostudies-literatured-Idose, d-Iduronic Acid, and d-Idonic Acid from d-Glucose via Seven-Carbon Sugars.PMC6832733Liu ZYoshihara AIzumori KWormald MRJenkinson SFFleet GWJfalsed-Idose, d-Iduronic Acid, and d-Idonic Acid from d-Glucose via Seven-Carbon Sugars.A practical synthesis of the very rare sugar d-idose and the stable building blocks for d-idose, d-iduronic, and d-idonic acids from ido-heptonic acid requires only isopropylidene protection, Shing silica gel-supported periodate cleavage of the C6-C7 bond of the heptonic acid, and selective reduction of C1 and/or C6. d-Idose is the most unstable of all the aldohexoses and a stable precursor which be stored and then converted under very mild conditions into d-idose is easily prepared.2019-01-01T00:00:00Z2019 Oct2025-04-18T23:34:56.431Z2020-05-21T19:29:52ZS-EPMC68327333163539710.3390/molecules24203758