biostudies-literatureUnknown9(1)Creel SCurrent extinction rates are comparable to five prior mass extinctions in the earth's history, and are strongly affected by human activities that have modified more than half of the earth's terrestrial surface. Increasing human activity restricts animal movements and isolates formerly connected populations, a particular concern for the conservation of large carnivores, but no prior research has used high throughput sequencing in a standardized manner to examine genetic connectivity for multiple species of large carnivores and multiple ecosystems. Here, we used RAD SNP genotypes to test for differences in connectivity between multiple ecosystems for African wild dogs (Lycaon pictus) and lions (Panthera leo), and to test correlations between genetic distance, geographic distance and landscapScientific reports16339https://www.ebi.ac.uk/biostudies/studies/S-EPMC6841969biostudies-literatureCarnivores, competition and genetic connectivity in the Anthropocene.PMC6841969Spong GBecker MSchiffthaler BChifunte CCreel SSimukonda CNorman AfalseCarnivores, competition and genetic connectivity in the Anthropocene.Current extinction rates are comparable to five prior mass extinctions in the earth's history, and are strongly affected by human activities that have modified more than half of the earth's terrestrial surface. Increasing human activity restricts animal movements and isolates formerly connected populations, a particular concern for the conservation of large carnivores, but no prior research has used high throughput sequencing in a standardized manner to examine genetic connectivity for multiple species of large carnivores and multiple ecosystems. Here, we used RAD SNP genotypes to test for differences in connectivity between multiple ecosystems for African wild dogs (Lycaon pictus) and lions (Panthera leo), and to test correlations between genetic distance, geographic distance and landscap2019-01-01T00:00:00Z2019 Nov2026-04-13T21:28:34.004Z2026-04-07T13:36:06.589ZS-EPMC68419693170501710.1038/s41598-019-52904-0