{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gobas FAPC"],"funding":["European Center for Silicones"],"pagination":["2065-2072"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6852268"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["38(9)"],"pubmed_abstract":["We illustrate that the Organisation for Economic Co-operation and Development guideline 305 (OECD-305) for growth-correcting bioconcentration factors (BCFs) and biomagnification factors (BMFs) violates the mass-balance assumption underlying the definition of BCFs and BMFs and provides unrealistic estimates of BCFs and BMFs of chemicals in nongrowing fish. We present and test alternative methods for growth-correcting BCFs and BMFs that maintain mass balance. We conclude that the OECD-305-recommended growth correction of BCFs and BMFs causes error, is unnecessary, and should be revisited. Environ Toxicol Chem 2019;38:2065-2072. © 2019 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals, Inc. on behalf of SETAC."],"journal":["Environmental toxicology and chemistry"],"pubmed_title":["Growth-Correcting the Bioconcentration Factor and Biomagnification Factor in Bioaccumulation Assessments."],"pmcid":["PMC6852268"],"funding_grant_id":["NA"],"pubmed_authors":["Lee YS","Gobas FAPC"],"additional_accession":[]},"is_claimable":false,"name":"Growth-Correcting the Bioconcentration Factor and Biomagnification Factor in Bioaccumulation Assessments.","description":"We illustrate that the Organisation for Economic Co-operation and Development guideline 305 (OECD-305) for growth-correcting bioconcentration factors (BCFs) and biomagnification factors (BMFs) violates the mass-balance assumption underlying the definition of BCFs and BMFs and provides unrealistic estimates of BCFs and BMFs of chemicals in nongrowing fish. We present and test alternative methods for growth-correcting BCFs and BMFs that maintain mass balance. We conclude that the OECD-305-recommended growth correction of BCFs and BMFs causes error, is unnecessary, and should be revisited. Environ Toxicol Chem 2019;38:2065-2072. © 2019 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals, Inc. on behalf of SETAC.","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Sep","modification":"2025-04-26T01:47:40.815Z","creation":"2020-05-21T19:20:26Z"},"accession":"S-EPMC6852268","cross_references":{"pubmed":["31162716"],"doi":["10.1002/etc.4509"]}}