{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(11)"],"submitter":["Chmiel C"],"funding":["“Gottfried und Julia Bangerter-Rhyner-Stiftung”, fund of the Swiss Academy of Medical Sciences","Thermo Fisher Scientific","IBDnet, Swiss Research and Communication Network on Inflammatory Bowel Disease"],"pubmed_abstract":["Background
Diagnosis of inflammatory bowel disease (IBD) in primary care (PC) is challenging and associated with a considerable diagnostic delay. Using a calprotectin test for any PC patient with abdominal complaints would cause significant costs. The 8-item-questionnaire CalproQuest was developed to increase the pre-test probability for a positive Calprotectin. It is a feasible instrument to assess IBD in PC, but has not yet been evaluated in clinical routine. This study, therefore, aimed to validate whether the CalproQuest increases pretest-probability for a positive fecal Calprotectin.Methods
Prospective diagnostic trial. The CalproQuest consists of 4 major and 4 minor questions suggestive for IBD. It is considered positive if ≥ 2 major or 1 major and 2 minor criteria ar"],"journal":["PloS one"],"pagination":["e0224961"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6872045"],"repository":["biostudies-literature"],"pubmed_title":["Can the CalproQuest predict a positive Calprotectin test? A prospective diagnostic study."],"pmcid":["PMC6872045"],"pubmed_authors":["Sulz MC","Senn O","Tandjung R","Scherz N","Chmiel C","Zahnd N","Vavricka S","Hasler S","Rosemann T","Rogler G"],"additional_accession":[]},"is_claimable":false,"name":"Can the CalproQuest predict a positive Calprotectin test? A prospective diagnostic study.","description":"Background
Diagnosis of inflammatory bowel disease (IBD) in primary care (PC) is challenging and associated with a considerable diagnostic delay. Using a calprotectin test for any PC patient with abdominal complaints would cause significant costs. The 8-item-questionnaire CalproQuest was developed to increase the pre-test probability for a positive Calprotectin. It is a feasible instrument to assess IBD in PC, but has not yet been evaluated in clinical routine. This study, therefore, aimed to validate whether the CalproQuest increases pretest-probability for a positive fecal Calprotectin.Methods
Prospective diagnostic trial. The CalproQuest consists of 4 major and 4 minor questions suggestive for IBD. It is considered positive if ≥ 2 major or 1 major and 2 minor criteria ar","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2025-04-04T13:27:57.091Z","creation":"2020-05-21T21:18:05Z"},"accession":"S-EPMC6872045","cross_references":{"pubmed":["31751360"],"doi":["10.1371/journal.pone.0224961"]}}