{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(1)"],"submitter":["Kwon H"],"funding":["Korea Centers for Disease Control and Prevention"],"pubmed_abstract":["ABO-incompatible (ABOi) and positive crossmatch (XM) kidney transplantation (KT) have been considered immunologically challenging. The present study analyzed the clinical outcomes in XM positive KT based on ABO incompatibility. We used data from the Korea Organ Transplantation Registry, a nationwide database, and a single-center registry. A total of 263 patients with positive XM were divided into an ABO compatible (ABOc) & XM positive (ABOc/XM+, n = 176) group and an ABOi & XM positive (ABOi/XM+, n = 87) group. The overall rejection rate one year after KT was significantly higher in the ABOi/XM+ group than in the ABOc/XM+ group (P < 0.01). A total of four mortalities occurred, all in the ABOi/XM+ patients (P < 0.01). There were no differences in surgical complications or the occurrence of "],"journal":["Scientific reports"],"pagination":["18229"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6890690"],"repository":["biostudies-literature"],"pubmed_title":["Effect of simultaneous presence of anti-blood group A/B and -HLA antibodies on clinical outcomes in kidney transplantation across positive crossmatch: a nationwide cohort study."],"pmcid":["PMC6890690"],"pubmed_authors":["Shin S","Jung CW","Kim MS","Kim CD","Jung JH","Lee KW","Choi S","Roh YN","Park JW","Chae DW","Kim JY","Kim YH","Park YH","Han SY","Lee JJ","Jeon JS","Kong JM","Kim SJ","Ko Y","Park SK","Kim DH","Seong EY","Cho HR","Yang J","Kwon OJ","Jeong KH","Korean Organ Transplantation Registry Study Group","Park JH","Lee SH","Kim JK","Lee DW","Ahn C","Kwon H","Lee DR","Lee SY","Choi JY","Han DJ","Choi BS","Park JB"],"additional_accession":[]},"is_claimable":false,"name":"Effect of simultaneous presence of anti-blood group A/B and -HLA antibodies on clinical outcomes in kidney transplantation across positive crossmatch: a nationwide cohort study.","description":"ABO-incompatible (ABOi) and positive crossmatch (XM) kidney transplantation (KT) have been considered immunologically challenging. The present study analyzed the clinical outcomes in XM positive KT based on ABO incompatibility. We used data from the Korea Organ Transplantation Registry, a nationwide database, and a single-center registry. A total of 263 patients with positive XM were divided into an ABO compatible (ABOc) & XM positive (ABOc/XM+, n = 176) group and an ABOi & XM positive (ABOi/XM+, n = 87) group. The overall rejection rate one year after KT was significantly higher in the ABOi/XM+ group than in the ABOc/XM+ group (P < 0.01). A total of four mortalities occurred, all in the ABOi/XM+ patients (P < 0.01). There were no differences in surgical complications or the occurrence of ","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Dec","modification":"2025-04-19T03:39:31.407Z","creation":"2020-05-21T21:23:49Z"},"accession":"S-EPMC6890690","cross_references":{"pubmed":["31796812"],"doi":["10.1038/s41598-019-54397-3"]}}