{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Crowe W"],"funding":["Invest Northern Ireland"],"pagination":["E2673"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6893523"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(11)"],"pubmed_abstract":["The World Cancer Research Fund (WCRF) 2007 stated that the consumption of processed meat is a convincing cause of colorectal cancer (CRC), and therefore, the public should avoid it entirely. Sodium nitrite has emerged as a putative candidate responsible for the CRC-inducing effects of processed meats. Sodium nitrite is purported to prevent the growth of Clostridium botulinum and other food-spoiling bacteria, but recent, contradictory peer-reviewed evidence has emerged, leading to media reports questioning the necessity of nitrite addition. To date, eleven preclinical studies have investigated the effect of consuming nitrite/nitrite-containing meat on the development of CRC, but the results do not provide an overall consensus. A sizable number of human clinical studies have investigated the"],"journal":["Nutrients"],"pubmed_title":["A Review of the In Vivo Evidence Investigating the Role of Nitrite Exposure from Processed Meat Consumption in the Development of Colorectal Cancer."],"pmcid":["PMC6893523"],"funding_grant_id":["N/A"],"pubmed_authors":["Crowe W","Green BD","Elliott CT"],"additional_accession":[]},"is_claimable":false,"name":"A Review of the In Vivo Evidence Investigating the Role of Nitrite Exposure from Processed Meat Consumption in the Development of Colorectal Cancer.","description":"The World Cancer Research Fund (WCRF) 2007 stated that the consumption of processed meat is a convincing cause of colorectal cancer (CRC), and therefore, the public should avoid it entirely. Sodium nitrite has emerged as a putative candidate responsible for the CRC-inducing effects of processed meats. Sodium nitrite is purported to prevent the growth of Clostridium botulinum and other food-spoiling bacteria, but recent, contradictory peer-reviewed evidence has emerged, leading to media reports questioning the necessity of nitrite addition. To date, eleven preclinical studies have investigated the effect of consuming nitrite/nitrite-containing meat on the development of CRC, but the results do not provide an overall consensus. A sizable number of human clinical studies have investigated the","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Nov","modification":"2025-05-29T21:37:52.392Z","creation":"2025-05-29T21:37:52.392Z"},"accession":"S-EPMC6893523","cross_references":{"pubmed":["31694233"],"doi":["10.3390/nu11112673"]}}