{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Maximo HJ"],"funding":["CNPq","Fapesp"],"pagination":["544"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6896422"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(1)"],"pubmed_abstract":["<h4>Background</h4>Phytophthora species secrete cytoplasmic effectors from a family named Crinkler (CRN), which are characterised by the presence of conserved specific domains in the N- and C-terminal regions. P. parasitica causes disease in a wide range of host plants, however the role of CRN effectors in these interactions remains unclear. Here, we aimed to: (i) identify candidate CRN encoding genes in P. parasitica genomes; (ii) evaluate the transcriptional expression of PpCRN (Phytophthora parasitica Crinkler candidate) during the P. parasitica interaction with Citrus sunki (high susceptible) and Poncirus trifoliata (resistant); and (iii) functionally characterize two PpCRNs in the model plant Nicotiana benthamiana.<h4>Results</h4>Our in silico analyses identified 80 putative PpCRN eff"],"journal":["BMC plant biology"],"pubmed_title":["PpCRN7 and PpCRN20 of Phythophthora parasitica regulate plant cell death leading to enhancement of host susceptibility."],"pmcid":["PMC6896422"],"funding_grant_id":["2015/14498-6","465450/2014-2","2014/50880-4"],"pubmed_authors":["Felizatti HL","Dias RO","Dalio RJD","Maximo HJ","Machado MA","Litholdo CG"],"additional_accession":[]},"is_claimable":false,"name":"PpCRN7 and PpCRN20 of Phythophthora parasitica regulate plant cell death leading to enhancement of host susceptibility.","description":"<h4>Background</h4>Phytophthora species secrete cytoplasmic effectors from a family named Crinkler (CRN), which are characterised by the presence of conserved specific domains in the N- and C-terminal regions. P. parasitica causes disease in a wide range of host plants, however the role of CRN effectors in these interactions remains unclear. Here, we aimed to: (i) identify candidate CRN encoding genes in P. parasitica genomes; (ii) evaluate the transcriptional expression of PpCRN (Phytophthora parasitica Crinkler candidate) during the P. parasitica interaction with Citrus sunki (high susceptible) and Poncirus trifoliata (resistant); and (iii) functionally characterize two PpCRNs in the model plant Nicotiana benthamiana.<h4>Results</h4>Our in silico analyses identified 80 putative PpCRN eff","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Dec","modification":"2026-05-03T13:10:23.265Z","creation":"2020-05-21T22:25:38Z"},"accession":"S-EPMC6896422","cross_references":{"pubmed":["31810451"],"doi":["10.1186/s12870-019-2129-8"]}}