biostudies-literatureUnknown13Hussain S<h4>Background</h4>Cancer is one of the chronic health conditions worldwide. Various therapeutically active compounds from medicinal plants were the current focus of this research in order to uncover a treatment regimen for cancer. <i>Anchusa arvensis (A. anchusa)</i> (L.) M.Bieb. contains many biologically active compounds.<h4>Methods</h4>In the current study, new ester 3-hydroxyoctyl -5- <i>trans</i>-docosenoate (compound-1) was isolated from the chloroform soluble fraction of <i>A. anchusa</i> using column chromatography. Using MTT assay, the anticancer effect of the compound was determined in human hepatocellular carcinoma cells (HepG-2) compared with normal epithelial cell line (Vero). DPPH and ABTS radical scavenging assays were performed to assess the antioxidant potential. The MoleDrug design, development and therapy4195-4205https://www.ebi.ac.uk/biostudies/studies/S-EPMC6911335biostudies-literatureIn Silico, Cytotoxic and Antioxidant Potential of Novel Ester, 3-hydroxyoctyl -5<i>- trans</i>-docosenoate Isolated from <i>Anchusa arvensis</i> (L.) M.Bieb. Against HepG-2 Cancer Cells.PMC6911335Ullah RHussain SAli Shah SAAman WShahat AAAyaz MWadood ANasr FAShah SMUllah FAli Shah AUfalseIn Silico, Cytotoxic and Antioxidant Potential of Novel Ester, 3-hydroxyoctyl -5<i>- trans</i>-docosenoate Isolated from <i>Anchusa arvensis</i> (L.) M.Bieb. Against HepG-2 Cancer Cells.<h4>Background</h4>Cancer is one of the chronic health conditions worldwide. Various therapeutically active compounds from medicinal plants were the current focus of this research in order to uncover a treatment regimen for cancer. <i>Anchusa arvensis (A. anchusa)</i> (L.) M.Bieb. contains many biologically active compounds.<h4>Methods</h4>In the current study, new ester 3-hydroxyoctyl -5- <i>trans</i>-docosenoate (compound-1) was isolated from the chloroform soluble fraction of <i>A. anchusa</i> using column chromatography. Using MTT assay, the anticancer effect of the compound was determined in human hepatocellular carcinoma cells (HepG-2) compared with normal epithelial cell line (Vero). DPPH and ABTS radical scavenging assays were performed to assess the antioxidant potential. The Mole2019-01-01T00:00:00Z20192025-04-18T17:01:21.241Z2020-11-19T13:22:58ZS-EPMC69113353184945110.2147/DDDT.S228971