biostudies-literatureBaker ENational Institute for Health Research (NIHR)Academy of Medical Sciences3-10https://www.ebi.ac.uk/biostudies/studies/S-EPMC6913574biostudies-literatureUnknown1<h4>Introduction</h4>Wide local excision and adjuvant radiotherapy is the standard of care for early breast cancer. For large tumours, however, mastectomy is frequently recommended as conventional breast-conserving techniques often result in poor cosmetic outcomes. Therapeutic mammaplasty (TM) may extend the boundaries of breast-conserving surgery by combining breast reduction and mastopexy techniques with tumour excision, preserving a natural breast shape and avoiding the need for mastectomy. The prevalence of this operative option among surgeons in the UK and its success rate are unknown. The TeaM study is a multicentre prospective study that aims to investigate the practice and outcomes of TM.<h4>Methods and analysis</h4>Breast centres performing TM will be invited to participate througInternational journal of surgery protocolsThe TeaM (<i>T</i>h<i>e</i>r<i>a</i>peutic <i>M</i>ammaplasty) study: Protocol for a prospective multi-centre cohort study to evaluate the practice and outcomes of therapeutic mammaplasty.PMC6913574CL-2012-25-503PB-PG-0214-33065AMS-SGCL8-PotterFairbrother PKim BBasu NRattay TTrickey AMammary Fold Academic and Research CollaborativeAggarwal SWilliams KTurton PPotter STeaM Steering GroupBaker EAchuthan RMacmillan RDGardiner MDSutton RHolcombe CJain AMurphy JRemoundos DBrock LIves CfalseThe TeaM (<i>T</i>h<i>e</i>r<i>a</i>peutic <i>M</i>ammaplasty) study: Protocol for a prospective multi-centre cohort study to evaluate the practice and outcomes of therapeutic mammaplasty.<h4>Introduction</h4>Wide local excision and adjuvant radiotherapy is the standard of care for early breast cancer. For large tumours, however, mastectomy is frequently recommended as conventional breast-conserving techniques often result in poor cosmetic outcomes. Therapeutic mammaplasty (TM) may extend the boundaries of breast-conserving surgery by combining breast reduction and mastopexy techniques with tumour excision, preserving a natural breast shape and avoiding the need for mastectomy. The prevalence of this operative option among surgeons in the UK and its success rate are unknown. The TeaM study is a multicentre prospective study that aims to investigate the practice and outcomes of TM.<h4>Methods and analysis</h4>Breast centres performing TM will be invited to participate throug2016-01-01T00:00:00Z20162025-04-04T20:45:52.001Z2021-02-25T09:44:40ZS-EPMC69135743185175710.1016/j.isjp.2016.08.001