{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["28"],"submitter":["Hirata CL"],"funding":["Japan Society for the Promotion of Science"],"pubmed_abstract":["This dataset is supplementary to the submitted research by Ref. [1]. RNAs were extracted from high molecular weight complexes, prepared with 100 kDa filtration of HEK293 Tet-on cells stably transfected with either F-HA-Txnip-V5-His or control vector. Cells were stimulated with 1 μg/mL doxycycline for 24 h, followed by overnight stimulation with 100 μM 4-thiouridine (4sU), 20 mM glucose, and 1 μM bortezomib for 14h. The extracted RNAs from Txnip overexpressing cells compared with control cells was analyzed by RNA-seq. Differentially expressed mRNAs, long noncoding RNAs (lncRNA) and transcripts of uncertain coding potential (TUCPs) are shown. Gene ontology and KEGG enrichment of these differential expressed RNAs is presented."],"journal":["Data in brief"],"pagination":["104893"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6926129"],"repository":["biostudies-literature"],"pubmed_title":["Dataset on the formation of Thioredoxin interacting protein (Txnip) containing redox sensitive high molecular weight nucleoprotein complexes."],"pmcid":["PMC6926129"],"pubmed_authors":["Masutani H","Hirata CL","Ito S"],"additional_accession":[]},"is_claimable":false,"name":"Dataset on the formation of Thioredoxin interacting protein (Txnip) containing redox sensitive high molecular weight nucleoprotein complexes.","description":"This dataset is supplementary to the submitted research by Ref. [1]. RNAs were extracted from high molecular weight complexes, prepared with 100 kDa filtration of HEK293 Tet-on cells stably transfected with either F-HA-Txnip-V5-His or control vector. Cells were stimulated with 1 μg/mL doxycycline for 24 h, followed by overnight stimulation with 100 μM 4-thiouridine (4sU), 20 mM glucose, and 1 μM bortezomib for 14h. The extracted RNAs from Txnip overexpressing cells compared with control cells was analyzed by RNA-seq. Differentially expressed mRNAs, long noncoding RNAs (lncRNA) and transcripts of uncertain coding potential (TUCPs) are shown. Gene ontology and KEGG enrichment of these differential expressed RNAs is presented.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Feb","modification":"2024-12-04T12:06:38.342Z","creation":"2020-05-22T01:16:02Z"},"accession":"S-EPMC6926129","cross_references":{"pubmed":["31890777"],"doi":["10.1016/j.dib.2019.104893"]}}