{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Levy R"],"funding":["NIDA NIH HHS","NIMH NIH HHS","National Institute of Mental Health"],"pagination":["424"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6935499"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(1)"],"pubmed_abstract":["<h4>Background</h4>Mental disorders are a leading cause of global disability, driven primarily by depression and anxiety. Most of the disease burden is in Low and Middle Income Countries (LMICs), where 75% of adults with mental disorders have no service access. Our research team has worked in western Kenya for nearly ten years. Primary care populations in Kenya have high prevalence of Major Depressive Disorder (MDD) and Posttraumatic Stress Disorder (PTSD). To address these treatment needs with a sustainable, scalable mental health care strategy, we are partnering with local and national mental health stakeholders in Kenya and Uganda to identify 1) evidence-based strategies for first-line and second-line treatment delivered by non-specialists integrated with primary care, 2) investigate pr"],"journal":["BMC psychiatry"],"pubmed_title":["Implementation research for public sector mental health care scale-up (SMART-DAPPER): a sequential multiple, assignment randomized trial (SMART) of non-specialist-delivered psychotherapy and/or medication for major depressive disorder and posttraumatic stress disorder (DAPPER) integrated with outpatient care clinics at a county hospital in Kenya."],"pmcid":["PMC6935499"],"funding_grant_id":["R01 MH115512","R01 DA039901","R01 MH113722"],"pubmed_authors":["Kahn JG","Nahum-Shani I","Onyango D","Blum K","Mathai M","Burger R","Rota G","Neylan TC","Ongeri L","Lukwata H","Bukusi D","Meffert SM","Cohen CR","Levy R","Chatterjee P","Njuguna S","Akena D","Otieno A","Aarons GA","McCulloch CE"],"additional_accession":[]},"is_claimable":false,"name":"Implementation research for public sector mental health care scale-up (SMART-DAPPER): a sequential multiple, assignment randomized trial (SMART) of non-specialist-delivered psychotherapy and/or medication for major depressive disorder and posttraumatic stress disorder (DAPPER) integrated with outpatient care clinics at a county hospital in Kenya.","description":"<h4>Background</h4>Mental disorders are a leading cause of global disability, driven primarily by depression and anxiety. Most of the disease burden is in Low and Middle Income Countries (LMICs), where 75% of adults with mental disorders have no service access. Our research team has worked in western Kenya for nearly ten years. Primary care populations in Kenya have high prevalence of Major Depressive Disorder (MDD) and Posttraumatic Stress Disorder (PTSD). To address these treatment needs with a sustainable, scalable mental health care strategy, we are partnering with local and national mental health stakeholders in Kenya and Uganda to identify 1) evidence-based strategies for first-line and second-line treatment delivered by non-specialists integrated with primary care, 2) investigate pr","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Dec","modification":"2025-04-04T10:43:17.937Z","creation":"2020-05-22T01:35:13Z"},"accession":"S-EPMC6935499","cross_references":{"pubmed":["31883526"],"doi":["10.1186/s12888-019-2395-x"]}}