{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kantele A"],"funding":["Office of Research and Development","Scandinavian Society for Antimicrobial Chemotherapy Foundation","U.S. Department of Veterans Affairs","Paulo Foundation","CSRD VA"],"pagination":["210-218"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6938974"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["70(2)"],"pubmed_abstract":["Background
One-third of the 100 million travelers to the tropics annually acquire extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-PE), with undefined clinical consequences.Methods
Symptoms suggesting Enterobacteriaceae infections were recorded prospectively among 430 Finnish travelers, 90 (21%) of whom acquired ESBL-PE abroad. ESBL-PE isolates underwent polymerase chain reaction-based detection of diarrheagenic Escherichia coli (DEC) pathotypes (enteroaggregative E. coli [EAEC], enteropathogenic E. coli [EPEC], enterotoxigenic E. coli [ETEC], enteroinvasive E. coli, and Shiga toxin-producing E. coli), and extraintestinal pathogenic/uropathogenic E. coli (ExPEC/UPEC). Laboratory-confirmed ESBL-PE infections were surveyed 5 years before and after trave"],"journal":["Clinical infectious diseases : an official publication of the Infectious Diseases Society of America"],"pubmed_title":["Despite Predominance of Uropathogenic/Extraintestinal Pathotypes Among Travel-acquired Extended-spectrum β-Lactamase-producing Escherichia coli, the Most Commonly Associated Clinical Manifestation Is Travelers' Diarrhea."],"pmcid":["PMC6938974"],"funding_grant_id":["1 I01 CX000920-01","2I01CX000920-04","I01 CX000920"],"pubmed_authors":["Mero S","Kantele A","Hakkinen IMK","Johnston BD","Laaveri T","Kirveskari J","Johnson JR"],"additional_accession":[]},"is_claimable":false,"name":"Despite Predominance of Uropathogenic/Extraintestinal Pathotypes Among Travel-acquired Extended-spectrum β-Lactamase-producing Escherichia coli, the Most Commonly Associated Clinical Manifestation Is Travelers' Diarrhea.","description":"Background
One-third of the 100 million travelers to the tropics annually acquire extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-PE), with undefined clinical consequences.Methods
Symptoms suggesting Enterobacteriaceae infections were recorded prospectively among 430 Finnish travelers, 90 (21%) of whom acquired ESBL-PE abroad. ESBL-PE isolates underwent polymerase chain reaction-based detection of diarrheagenic Escherichia coli (DEC) pathotypes (enteroaggregative E. coli [EAEC], enteropathogenic E. coli [EPEC], enterotoxigenic E. coli [ETEC], enteroinvasive E. coli, and Shiga toxin-producing E. coli), and extraintestinal pathogenic/uropathogenic E. coli (ExPEC/UPEC). Laboratory-confirmed ESBL-PE infections were surveyed 5 years before and after trave","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jan","modification":"2025-04-19T08:54:06.218Z","creation":"2020-05-22T07:15:31Z"},"accession":"S-EPMC6938974","cross_references":{"pubmed":["31034006"],"doi":["10.1093/cid/ciz182"]}}