{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Boyle CJ"],"funding":["Imperial College London","Engineering and Physical Sciences Research Council"],"pagination":["e0227064"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6941906"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(1)"],"pubmed_abstract":["When immobile or neuropathic patients are supported by beds or chairs, their soft tissues undergo deformations that can cause pressure ulcers. Current support surfaces that redistribute under-body pressures at vulnerable body sites have not succeeded in reducing pressure ulcer prevalence. Here we show that adding a supporting lateral pressure can counter-act the deformations induced by under-body pressure, and that this 'pressure equalisation' approach is a more effective way to reduce ulcer-inducing deformations than current approaches based on redistributing under-body pressure. A finite element model of the seated pelvis predicts that applying a lateral pressure to the soft tissue reduces peak von Mises stress in the deep tissue by a factor of 2.4 relative to a standard cushion (from 113 kPa to 47 kPa)-a greater effect than that achieved by using a more conformable cushion, which reduced von Mises stress to 75 kPa. Combining both a conformable cushion and lateral pressure reduced peak von Mises stresses to 25 kPa. The ratio of peak lateral pressure to peak under-body pressure was shown to regulate deep tissue stress better than under-body pressure alone. By optimising the magnitude and position of lateral pressure, tissue deformations can be reduced to that induced when suspended in a fluid. Our results explain the lack of efficacy in current support surfaces and suggest a new approach to designing and evaluating support surfaces: ensuring sufficient lateral pressure is applied to counter-act under-body pressure."],"journal":["PloS one"],"pubmed_title":["Lateral pressure equalisation as a principle for designing support surfaces to prevent deep tissue pressure ulcers."],"pmcid":["PMC6941906"],"funding_grant_id":["EP/N026845/1","Proof of Concept Grant 2017"],"pubmed_authors":["Masouros SD","Higgins CA","Pandelani T","Boyle CJ","Masen MA","Carpanen D"],"additional_accession":[]},"is_claimable":false,"name":"Lateral pressure equalisation as a principle for designing support surfaces to prevent deep tissue pressure ulcers.","description":"When immobile or neuropathic patients are supported by beds or chairs, their soft tissues undergo deformations that can cause pressure ulcers. Current support surfaces that redistribute under-body pressures at vulnerable body sites have not succeeded in reducing pressure ulcer prevalence. Here we show that adding a supporting lateral pressure can counter-act the deformations induced by under-body pressure, and that this 'pressure equalisation' approach is a more effective way to reduce ulcer-inducing deformations than current approaches based on redistributing under-body pressure. A finite element model of the seated pelvis predicts that applying a lateral pressure to the soft tissue reduces peak von Mises stress in the deep tissue by a factor of 2.4 relative to a standard cushion (from 113 kPa to 47 kPa)-a greater effect than that achieved by using a more conformable cushion, which reduced von Mises stress to 75 kPa. Combining both a conformable cushion and lateral pressure reduced peak von Mises stresses to 25 kPa. The ratio of peak lateral pressure to peak under-body pressure was shown to regulate deep tissue stress better than under-body pressure alone. By optimising the magnitude and position of lateral pressure, tissue deformations can be reduced to that induced when suspended in a fluid. Our results explain the lack of efficacy in current support surfaces and suggest a new approach to designing and evaluating support surfaces: ensuring sufficient lateral pressure is applied to counter-act under-body pressure.","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019","modification":"2024-11-20T00:37:32.209Z","creation":"2020-05-22T07:27:40Z"},"accession":"S-EPMC6941906","cross_references":{"pubmed":["31899778"],"doi":["10.1371/journal.pone.0227064"]}}