biostudies-literatureUnknown10(1)Spano RGrafting of commercial tomato varieties and hybrids on the tomato ecotype Manduria resulted in high levels of tolerance to the infection of Sw5 resistance-breaking strains of tomato spotted wilt virus and of severe cucumber mosaic virus strains supporting hypervirulent satellite RNAs that co-determine stunting and necrotic phenotypes in tomato. To decipher the basis of such tolerance, here we used a RNAseq analysis to study the transcriptome profiles of the Manduria ecotype and of the susceptible variety UC82, and of their graft combinations, exposed or not to infection of the potato virus Y recombinant strain PVY^C-to. The analysis identified graft- and virus-responsive mRNAs differentially expressed in UC82 and Manduria, which led to an overall suitable level of tolerance to viScientific reports2538https://www.ebi.ac.uk/biostudies/studies/S-EPMC7018947biostudies-literatureGrafting alters tomato transcriptome and enhances tolerance to an airborne virus infection.PMC7018947Mule GFerrara MMontemurro CMascia TSpano RGallitelli DfalseGrafting alters tomato transcriptome and enhances tolerance to an airborne virus infection.Grafting of commercial tomato varieties and hybrids on the tomato ecotype Manduria resulted in high levels of tolerance to the infection of Sw5 resistance-breaking strains of tomato spotted wilt virus and of severe cucumber mosaic virus strains supporting hypervirulent satellite RNAs that co-determine stunting and necrotic phenotypes in tomato. To decipher the basis of such tolerance, here we used a RNAseq analysis to study the transcriptome profiles of the Manduria ecotype and of the susceptible variety UC82, and of their graft combinations, exposed or not to infection of the potato virus Y recombinant strain PVY^C-to. The analysis identified graft- and virus-responsive mRNAs differentially expressed in UC82 and Manduria, which led to an overall suitable level of tolerance to vi2020-01-01T00:00:00Z2020 Feb2026-05-07T14:34:22.183Z2020-05-22T10:43:05ZS-EPMC70189473205492010.1038/s41598-020-59421-5