{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nazareth T"],"funding":["Fundação para a Ciência e Tecnologia"],"pagination":["348-365"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7034073"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(1)"],"pubmed_abstract":["The release of modified mosquitoes to suppress/replace vectors constitutes a promising tool for vector control and disease prevention. Evidence regarding these innovative modification techniques is scarce and disperse. This work conducted a systematic review, gathering and analysing research articles from PubMed and Biblioteca Virtual em Saúde databases whose results report efficacy and non-target effects of using modified insects for disease prevention, until 2016. More than 1500 publications were screened and 349 were analysed. Only 12/3.4% articles reported field-based evidence and 41/11.7% covered modification strategies' post-release efficacy. Variability in the effective results (90/25.7%) questioned its reproducibility in different settings. We also found publications reporting reve"],"journal":["Emerging microbes & infections"],"pubmed_title":["What happens when we modify mosquitoes for disease prevention? A systematic review."],"pmcid":["PMC7034073"],"funding_grant_id":["PTDC/IVC – ESC T/2486/2014, UID/Multi/04413/2019, WARDEN – PTDC/SAU-PUB/30089/2017"],"pubmed_authors":["Moutinho A","Seixas G","Craveiro I","Goncalves C","Teodosio R","Sousa CA","Nazareth T","Goncalves L"],"additional_accession":[]},"is_claimable":false,"name":"What happens when we modify mosquitoes for disease prevention? A systematic review.","description":"The release of modified mosquitoes to suppress/replace vectors constitutes a promising tool for vector control and disease prevention. Evidence regarding these innovative modification techniques is scarce and disperse. This work conducted a systematic review, gathering and analysing research articles from PubMed and Biblioteca Virtual em Saúde databases whose results report efficacy and non-target effects of using modified insects for disease prevention, until 2016. More than 1500 publications were screened and 349 were analysed. Only 12/3.4% articles reported field-based evidence and 41/11.7% covered modification strategies' post-release efficacy. Variability in the effective results (90/25.7%) questioned its reproducibility in different settings. We also found publications reporting reve","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-05-29T20:31:37.33Z","creation":"2025-05-29T20:31:37.33Z"},"accession":"S-EPMC7034073","cross_references":{"pubmed":["32041484"],"doi":["10.1080/22221751.2020.1722035"]}}