{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lam CSY"],"funding":["Hoya Corporation"],"pagination":["363-368"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7041503"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["104(3)"],"pubmed_abstract":["<h4>Aim</h4>To determine if 'Defocus Incorporated Multiple Segments' (DIMS) spectacle lenses slow childhood myopia progression.<h4>Methods</h4>A 2-year double-masked randomised controlled trial was carried out in 183 Chinese children aged 8-13 years, with myopia between -1.00 and -5.00 D and astigmatism ≤1.50 D. Children were randomly assigned to wear DIMS (n=93) or single vision (SV) spectacle lenses (n=90). DIMS lens incorporated multiple segments with myopic defocus of +3.50 D. Refractive error (cycloplegic autorefraction) and axial length were measured at 6month intervals.<h4>Results</h4>160 children completed the study, n=79 in the DIMS group and n=81 in the SV group. Average (SE) myopic progressions over 2 years were -0.41±0.06 D in the DIMS group and -0.85±0.08 D in the SV group. Me"],"journal":["The British journal of ophthalmology"],"pubmed_title":["Defocus Incorporated Multiple Segments (DIMS) spectacle lenses slow myopia progression: a 2-year randomised clinical trial."],"pmcid":["PMC7041503"],"funding_grant_id":["collaborative research PolyU grant H-ZG3B &amp; 1-87LK"],"pubmed_authors":["Tse DY","Qi H","Tang WC","To CH","Chun RKM","Lee RPK","Hatanaka T","Lam CSY","Hasegawa K"],"additional_accession":[]},"is_claimable":false,"name":"Defocus Incorporated Multiple Segments (DIMS) spectacle lenses slow myopia progression: a 2-year randomised clinical trial.","description":"<h4>Aim</h4>To determine if 'Defocus Incorporated Multiple Segments' (DIMS) spectacle lenses slow childhood myopia progression.<h4>Methods</h4>A 2-year double-masked randomised controlled trial was carried out in 183 Chinese children aged 8-13 years, with myopia between -1.00 and -5.00 D and astigmatism ≤1.50 D. Children were randomly assigned to wear DIMS (n=93) or single vision (SV) spectacle lenses (n=90). DIMS lens incorporated multiple segments with myopic defocus of +3.50 D. Refractive error (cycloplegic autorefraction) and axial length were measured at 6month intervals.<h4>Results</h4>160 children completed the study, n=79 in the DIMS group and n=81 in the SV group. Average (SE) myopic progressions over 2 years were -0.41±0.06 D in the DIMS group and -0.85±0.08 D in the SV group. Me","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Mar","modification":"2026-06-16T03:13:20.399Z","creation":"2026-06-16T03:07:19.502Z"},"accession":"S-EPMC7041503","cross_references":{"pubmed":["31142465"],"doi":["10.1136/bjophthalmol-2018-313739"]}}