biostudies-literatureBurghardt JBundesministerium für Bildung und Forschunge034220https://www.ebi.ac.uk/biostudies/studies/S-EPMC7045246biostudies-literatureUnknown10(2)<h4>Introduction</h4>Mental health is marked by gender differences. We formed a multi-cohort consortium to perform GEnder-Sensitive Analyses of mental health trajectories and study their implications for prevention (GESA). GESA aims at (1) identifying gender differences regarding symptoms and trajectories of mental health over the lifespan; (2) determining gender differences regarding the prevalence, impact of risk and protective factors; and (3) determining effects of mental health on primary and secondary outcomes (eg, quality of life, healthcare behaviour and utilisation).<h4>Methods and analysis</h4>We plan to perform secondary analyses on three major, ongoing, population-based, longitudinal cohorts (Gutenberg Health-Study (GHS), Study of Health in Pomerania (SHIP), Cooperative Health BMJ openA multi-cohort consortium for GEnder-Sensitive Analyses of mental health trajectories and implications for prevention (GESA) in the general population in Germany.PMC704524601GL1718ASchomerus GBinder HWild PSBurghardt JGrabe HBrahler EKruse JBeutel MEOtten DTibubos ANLadwig KHfalseA multi-cohort consortium for GEnder-Sensitive Analyses of mental health trajectories and implications for prevention (GESA) in the general population in Germany.<h4>Introduction</h4>Mental health is marked by gender differences. We formed a multi-cohort consortium to perform GEnder-Sensitive Analyses of mental health trajectories and study their implications for prevention (GESA). GESA aims at (1) identifying gender differences regarding symptoms and trajectories of mental health over the lifespan; (2) determining gender differences regarding the prevalence, impact of risk and protective factors; and (3) determining effects of mental health on primary and secondary outcomes (eg, quality of life, healthcare behaviour and utilisation).<h4>Methods and analysis</h4>We plan to perform secondary analyses on three major, ongoing, population-based, longitudinal cohorts (Gutenberg Health-Study (GHS), Study of Health in Pomerania (SHIP), Cooperative Health 2020-01-01T00:00:00Z2020 Feb2025-04-05T08:54:05.541Z2020-05-22T12:41:52ZS-EPMC70452463210281910.1136/bmjopen-2019-034220