biostudies-literatureLiu WYNHLBI NIH HHSNIGMS NIH HHS158-168https://www.ebi.ac.uk/biostudies/studies/S-EPMC7055489biostudies-literatureUnknown65(2)<h4>Background</h4>The inherent stride-to-stride fluctuations during walking are altered in the aging population and could provide insight into gait impairments and falls in patients with COPD. Stride-to-stride fluctuations are quantified two ways: variability of the fluctuations (eg, standard deviation), and movement patterns within the fluctuations. Our objective was to investigate stride-to-stride fluctuations by evaluating the variability and movement patterns of lower limb joints in subjects with COPD compared to subjects without COPD as control subjects.<h4>Methods</h4>In this cross-sectional study, 22 subjects with COPD (age 63 ± 9 y; FEV₁ 54 ± 19% predicted) and 22 control subjects (age 62 ± 9 y; FEV₁ 95 ± 18% predicted) walked for 3 min on a treadmill while tRespiratory careSubjects With COPD Walk With Less Consistent Organization of Movement Patterns of the Lower Extremity.PMC7055489L30 HL129255P20 GM109090Schmid KKMeijer KSpruit MALiu WYYentes JMfalseSubjects With COPD Walk With Less Consistent Organization of Movement Patterns of the Lower Extremity.<h4>Background</h4>The inherent stride-to-stride fluctuations during walking are altered in the aging population and could provide insight into gait impairments and falls in patients with COPD. Stride-to-stride fluctuations are quantified two ways: variability of the fluctuations (eg, standard deviation), and movement patterns within the fluctuations. Our objective was to investigate stride-to-stride fluctuations by evaluating the variability and movement patterns of lower limb joints in subjects with COPD compared to subjects without COPD as control subjects.<h4>Methods</h4>In this cross-sectional study, 22 subjects with COPD (age 63 ± 9 y; FEV₁ 54 ± 19% predicted) and 22 control subjects (age 62 ± 9 y; FEV₁ 95 ± 18% predicted) walked for 3 min on a treadmill while t2020-01-01T00:00:00Z2020 Feb2025-04-29T11:29:06.039Z2025-04-06T19:53:27.805ZS-EPMC70554893171919310.4187/respcare.06743