biostudies-literatureXia HShanghai Agriculture Applied Technology Development Programthe Youth Talent Development Project supported by the Shanghai Municipal Agriculture Commission 2017Shanghai Natural Science Foundation232https://www.ebi.ac.uk/biostudies/studies/S-EPMC7071783biostudies-literatureUnknown21(1)<h4>Background</h4>Plant miRNAs play crucial roles in responses to drought and developmental processes. It is essential to understand the association of miRNAs with drought-tolerance (DT), as well as their impacts on growth, development, and reproduction (GDP). This will facilitate our utilization of rice miRNAs in breeding.<h4>Results</h4>In this study, we investigated the time course of miRNA responses to a long-term drought among six rice genotypes by high-throughput sequencing. In total, 354 conserved miRNAs were drought responsive, representing obvious genotype- and stage-dependent patterns. The drought-responsive miRNAs (DRMs) formed complex regulatory network via their coexpression and direct/indirect impacts on the rice transcriptome. Based on correlation analyses, 211 DRMs were prBMC genomicsTemporal responses of conserved miRNAs to drought and their associations with drought tolerance and productivity in rice.PMC707178317ZR14255002017-1-332017-02-08-00-08-F00071Xia HXiong JYu SChen LLuo LMa XKong DfalseTemporal responses of conserved miRNAs to drought and their associations with drought tolerance and productivity in rice.<h4>Background</h4>Plant miRNAs play crucial roles in responses to drought and developmental processes. It is essential to understand the association of miRNAs with drought-tolerance (DT), as well as their impacts on growth, development, and reproduction (GDP). This will facilitate our utilization of rice miRNAs in breeding.<h4>Results</h4>In this study, we investigated the time course of miRNA responses to a long-term drought among six rice genotypes by high-throughput sequencing. In total, 354 conserved miRNAs were drought responsive, representing obvious genotype- and stage-dependent patterns. The drought-responsive miRNAs (DRMs) formed complex regulatory network via their coexpression and direct/indirect impacts on the rice transcriptome. Based on correlation analyses, 211 DRMs were pr2020-01-01T00:00:00Z2020 Mar2026-05-02T22:38:09.745Z2020-05-22T13:27:36ZS-EPMC70717833217123210.1186/s12864-020-6646-5