{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["160(11)"],"submitter":["Chen YN"],"pubmed_abstract":["Turkey flocks have experienced turkey coronaviral enteritis sporadically in the United States since the 1990s. Twenty-four field isolates of turkey coronavirus (TCoV) from multiple states in the United States were recovered from 1994 to 2010 to determine the genetic relationships among them. The entire spike (S) gene of each TCoV isolate was amplified and sequenced. Pairwise comparisons were performed using the Clustal W program, revealing 90.0% to 98.4% sequence identity in the full-length S protein, 77.6% to 96.6% in the amino terminus of the S1 subunit (containing one hypervariable region in S1a), and 92.1% to 99.3% in the S2 subunit at the deduced amino acid sequence level. The conserved motifs, including two cleavage recognition sequences of the S protein, two heptad repeats, the tran"],"journal":["Archives of virology"],"pagination":["2719-26"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7086652"],"repository":["biostudies-literature"],"pubmed_title":["Genotyping of turkey coronavirus field isolates from various geographic locations in the Unites States based on the spike gene."],"pmcid":["PMC7086652"],"pubmed_authors":["Ababneh MM","Loa CC","Chen YN","Wu CC","Lin TL"],"additional_accession":[]},"is_claimable":false,"name":"Genotyping of turkey coronavirus field isolates from various geographic locations in the Unites States based on the spike gene.","description":"Turkey flocks have experienced turkey coronaviral enteritis sporadically in the United States since the 1990s. Twenty-four field isolates of turkey coronavirus (TCoV) from multiple states in the United States were recovered from 1994 to 2010 to determine the genetic relationships among them. The entire spike (S) gene of each TCoV isolate was amplified and sequenced. Pairwise comparisons were performed using the Clustal W program, revealing 90.0% to 98.4% sequence identity in the full-length S protein, 77.6% to 96.6% in the amino terminus of the S1 subunit (containing one hypervariable region in S1a), and 92.1% to 99.3% in the S2 subunit at the deduced amino acid sequence level. The conserved motifs, including two cleavage recognition sequences of the S protein, two heptad repeats, the tran","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Nov","modification":"2026-04-29T17:40:42.634Z","creation":"2020-05-22T14:25:00Z"},"accession":"S-EPMC7086652","cross_references":{"pubmed":["26254026"],"doi":["10.1007/s00705-015-2556-2"]}}