biostudies-literatureUnknown37(3)Sbarigia UJanssen Scientific Affairs, LLC<h4>Introduction</h4>This study aimed to characterize chronic hepatitis B (CHB)-infected patients and estimate the association between nucleos(t)ide analogue (NA) persistence and economic outcomes using data from the Veterans Health Administration (VHA) database.<h4>Methods</h4>Patients (at least 18 years of age) with two or more claims for CHB and at least one pharmacy claim for NA were identified using VHA data from 1 April 2013 to 31 March 2018. The index date was the first NA prescription fill date during 1 October 2014 to 31 March 2017. Persistence and non-persistence to NA treatment were assessed during the first 2 years post index date. Non-persistence was defined as at least one failure to refill medication within 30 days from the run-out date. Generalized linear models were used tAdvances in therapy1156-1172https://www.ebi.ac.uk/biostudies/studies/S-EPMC7089729biostudies-literatureEvaluating the Effect of Standard of Care Treatment on Burden of Chronic Hepatitis B: A Retrospective Analysis of the United States Veterans Population.PMC7089729Katz EGColasurdo JXie LSah JSylvester SSbarigia UKariburyo FfalseEvaluating the Effect of Standard of Care Treatment on Burden of Chronic Hepatitis B: A Retrospective Analysis of the United States Veterans Population.<h4>Introduction</h4>This study aimed to characterize chronic hepatitis B (CHB)-infected patients and estimate the association between nucleos(t)ide analogue (NA) persistence and economic outcomes using data from the Veterans Health Administration (VHA) database.<h4>Methods</h4>Patients (at least 18 years of age) with two or more claims for CHB and at least one pharmacy claim for NA were identified using VHA data from 1 April 2013 to 31 March 2018. The index date was the first NA prescription fill date during 1 October 2014 to 31 March 2017. Persistence and non-persistence to NA treatment were assessed during the first 2 years post index date. Non-persistence was defined as at least one failure to refill medication within 30 days from the run-out date. Generalized linear models were used t2020-01-01T00:00:00Z2020 Mar2025-04-18T18:39:35.955Z2020-05-22T14:24:41ZS-EPMC70897293200923210.1007/s12325-020-01240-1