{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["71(6)"],"submitter":["Galindo-Trigo S"],"funding":["Biotechnology and Biological Sciences Research Council"],"pubmed_abstract":["The kinesin family is greatly expanded in plants compared with animals and, with more than a third up-regulated in expression during cell division, it has been suggested that this expansion facilitated complex plant-specific cytoskeletal rearrangements. The cell cycle-regulated kinesins include two with an N-terminal malectin domain, a protein domain that has been shown to bind polysaccharides and peptides when found extracellularly in receptor-like kinases. Although malectin domain kinesins are evolutionarily deep rooted, their function in plants remains unclear. Here we show that loss of MALECTIN DOMAIN KINESIN 2 (MDKIN2) results in stochastic developmental defects in pollen, embryo, and endosperm. High rates of seed abnormalities and abortion occur in mdkin2 mutants through a partial ma"],"journal":["Journal of experimental botany"],"pagination":["1828-1841"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7094084"],"repository":["biostudies-literature"],"pubmed_title":["A malectin domain kinesin functions in pollen and seed development in Arabidopsis."],"pmcid":["PMC7094084"],"pubmed_authors":["Galindo-Trigo S","Grand TM","Smith LM","Voigt CA"],"additional_accession":[]},"is_claimable":false,"name":"A malectin domain kinesin functions in pollen and seed development in Arabidopsis.","description":"The kinesin family is greatly expanded in plants compared with animals and, with more than a third up-regulated in expression during cell division, it has been suggested that this expansion facilitated complex plant-specific cytoskeletal rearrangements. The cell cycle-regulated kinesins include two with an N-terminal malectin domain, a protein domain that has been shown to bind polysaccharides and peptides when found extracellularly in receptor-like kinases. Although malectin domain kinesins are evolutionarily deep rooted, their function in plants remains unclear. Here we show that loss of MALECTIN DOMAIN KINESIN 2 (MDKIN2) results in stochastic developmental defects in pollen, embryo, and endosperm. High rates of seed abnormalities and abortion occur in mdkin2 mutants through a partial ma","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Mar","modification":"2026-05-08T06:16:47.01Z","creation":"2025-05-29T19:04:42.498Z"},"accession":"S-EPMC7094084","cross_references":{"pubmed":["31950166"],"doi":["10.1093/jxb/eraa023"]}}