{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5(11)"],"submitter":["Omer WE"],"funding":["Institute of Nanotechnology, Kafrelsheikh University","Dr. Mohamed S. Attia Lab, Ain Shams University"],"pubmed_abstract":["We developed a novel, simple, sensitive, accurate, and precise method for the determination of calcitonin in different serum samples with medullar thyroid carcinoma. The designed flower-like thin film gold nanoparticles doped in a sol-gel/polyethylene glycol mold are used as an optical biosensor for the efficient determination of calcitonin. The sensor was characterized by transmission electron microscopy, scanning electron microscopy, X-ray diffraction, energy-dispersive X-ray microanalysis, and Fourier-transform infrared spectroscopy. The efficiency of the considered bio-sensor is done using the quencher calcitonin of the emission band at 360 nm of biomarker obtained at λ<sub>ex</sub> = 333 nm in acetonitrile solvent. The sensing mechanism was based on fluorescence resonance energy trans"],"journal":["ACS omega"],"pagination":["5629-5637"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7097903"],"repository":["biostudies-literature"],"pubmed_title":["Highly Efficient Gold Nano-Flower Optical Biosensor Doped in a Sol-Gel/PEG Matrix for the Determination of a Calcitonin Biomarker in Different Serum Samples."],"pmcid":["PMC7097903"],"pubmed_authors":["Omer WE","Elsaady MM","Youssef AO","Attia MS","El-Kemary MA","Gouda AA","Abou-Omar MN","Sayqal AA"],"additional_accession":[]},"is_claimable":false,"name":"Highly Efficient Gold Nano-Flower Optical Biosensor Doped in a Sol-Gel/PEG Matrix for the Determination of a Calcitonin Biomarker in Different Serum Samples.","description":"We developed a novel, simple, sensitive, accurate, and precise method for the determination of calcitonin in different serum samples with medullar thyroid carcinoma. The designed flower-like thin film gold nanoparticles doped in a sol-gel/polyethylene glycol mold are used as an optical biosensor for the efficient determination of calcitonin. The sensor was characterized by transmission electron microscopy, scanning electron microscopy, X-ray diffraction, energy-dispersive X-ray microanalysis, and Fourier-transform infrared spectroscopy. The efficiency of the considered bio-sensor is done using the quencher calcitonin of the emission band at 360 nm of biomarker obtained at λ<sub>ex</sub> = 333 nm in acetonitrile solvent. The sensing mechanism was based on fluorescence resonance energy trans","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Mar","modification":"2025-04-20T01:39:51.305Z","creation":"2020-05-22T15:36:06Z"},"accession":"S-EPMC7097903","cross_references":{"pubmed":["32226838"],"doi":["10.1021/acsomega.9b02833"]}}