biostudies-literatureZhao HNational Natural Science Foundation of Chinae031191https://www.ebi.ac.uk/biostudies/studies/S-EPMC7103794biostudies-literatureUnknown10(3)<h4>Objective</h4>We aimed to evaluate the validity of an algorithm to classify diagnoses according to the appropriateness of outpatient antibiotic use in the context of Chinese free text.<h4>Setting and participants</h4>A random sample of 10 000 outpatient visits was selected between January and April 2018 from a national database for monitoring rational use of drugs, which included data from 194 secondary and tertiary hospitals in China.<h4>Research design</h4>Diagnoses for outpatient visits were classified as tier 1 if associated with at least one condition that 'always' justified antibiotic use; as tier 2 if associated with at least one condition that only 'sometimes' justified antibiotic use but no conditions that 'always' justified antibiotic use; or as tier 3 if associated with onlyBMJ openValidation of an algorithm to evaluate the appropriateness of outpatient antibiotic prescribing using big data of Chinese diagnosis text.PMC7103794819731468147306791646107Zhuo LZhang ZZhan SYing YZhang MBian JYao XLi LWei LCao BZhao HfalseValidation of an algorithm to evaluate the appropriateness of outpatient antibiotic prescribing using big data of Chinese diagnosis text.<h4>Objective</h4>We aimed to evaluate the validity of an algorithm to classify diagnoses according to the appropriateness of outpatient antibiotic use in the context of Chinese free text.<h4>Setting and participants</h4>A random sample of 10 000 outpatient visits was selected between January and April 2018 from a national database for monitoring rational use of drugs, which included data from 194 secondary and tertiary hospitals in China.<h4>Research design</h4>Diagnoses for outpatient visits were classified as tier 1 if associated with at least one condition that 'always' justified antibiotic use; as tier 2 if associated with at least one condition that only 'sometimes' justified antibiotic use but no conditions that 'always' justified antibiotic use; or as tier 3 if associated with only2020-01-01T00:00:00Z2020 Mar2026-05-07T07:28:25.125Z2026-04-29T03:08:49.795ZS-EPMC71037943219829610.1136/bmjopen-2019-031191