{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(3)"],"submitter":["Adeniji SE"],"pubmed_abstract":["Mycobacterium tuberculosis has instigated a serious challenge toward the effective treatment of tuberculosis. The reoccurrence of the resistant strains of the disease to accessible drugs/medications has mandate for the development of more effective anti-tubercular agents with efficient activities. Time expended and costs in discovering and synthesizing new hypothetical drugs with improved biological activity have been a major challenge toward the treatment of multi-drug resistance strain M. tuberculosis (TB). Meanwhile, to solve the problem stated, a new approach i.e. QSAR which establish connection between novel drugs with a better biological against M. tuberculosis is adopted. The anti-tubercular model established in this study to forecast the biological activities of some anti-tubercula"],"journal":["Heliyon"],"pagination":["e03639"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7114754"],"repository":["biostudies-literature"],"pubmed_title":["Quantum modelling and molecular docking evaluation of some selected quinoline derivatives as anti-tubercular agents."],"pmcid":["PMC7114754"],"pubmed_authors":["Adamu Shallangwa G","Ebuka Arthur D","Abdullahi M","Mahmoud AY","Haruna A","Adeniji SE"],"additional_accession":[]},"is_claimable":false,"name":"Quantum modelling and molecular docking evaluation of some selected quinoline derivatives as anti-tubercular agents.","description":"Mycobacterium tuberculosis has instigated a serious challenge toward the effective treatment of tuberculosis. The reoccurrence of the resistant strains of the disease to accessible drugs/medications has mandate for the development of more effective anti-tubercular agents with efficient activities. Time expended and costs in discovering and synthesizing new hypothetical drugs with improved biological activity have been a major challenge toward the treatment of multi-drug resistance strain M. tuberculosis (TB). Meanwhile, to solve the problem stated, a new approach i.e. QSAR which establish connection between novel drugs with a better biological against M. tuberculosis is adopted. The anti-tubercular model established in this study to forecast the biological activities of some anti-tubercula","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Mar","modification":"2025-04-04T07:20:05.989Z","creation":"2020-05-22T16:21:04Z"},"accession":"S-EPMC7114754","cross_references":{"pubmed":["32258484"],"doi":["10.1016/j.heliyon.2020.e03639"]}}