biostudies-literatureUnknown6(3)Adeniji SEMycobacterium tuberculosis has instigated a serious challenge toward the effective treatment of tuberculosis. The reoccurrence of the resistant strains of the disease to accessible drugs/medications has mandate for the development of more effective anti-tubercular agents with efficient activities. Time expended and costs in discovering and synthesizing new hypothetical drugs with improved biological activity have been a major challenge toward the treatment of multi-drug resistance strain M. tuberculosis (TB). Meanwhile, to solve the problem stated, a new approach i.e. QSAR which establish connection between novel drugs with a better biological against M. tuberculosis is adopted. The anti-tubercular model established in this study to forecast the biological activities of some anti-tuberculaHeliyone03639https://www.ebi.ac.uk/biostudies/studies/S-EPMC7114754biostudies-literatureQuantum modelling and molecular docking evaluation of some selected quinoline derivatives as anti-tubercular agents.PMC7114754Adamu Shallangwa GEbuka Arthur DAbdullahi MMahmoud AYHaruna AAdeniji SEfalseQuantum modelling and molecular docking evaluation of some selected quinoline derivatives as anti-tubercular agents.Mycobacterium tuberculosis has instigated a serious challenge toward the effective treatment of tuberculosis. The reoccurrence of the resistant strains of the disease to accessible drugs/medications has mandate for the development of more effective anti-tubercular agents with efficient activities. Time expended and costs in discovering and synthesizing new hypothetical drugs with improved biological activity have been a major challenge toward the treatment of multi-drug resistance strain M. tuberculosis (TB). Meanwhile, to solve the problem stated, a new approach i.e. QSAR which establish connection between novel drugs with a better biological against M. tuberculosis is adopted. The anti-tubercular model established in this study to forecast the biological activities of some anti-tubercula2020-01-01T00:00:00Z2020 Mar2025-04-04T07:20:05.989Z2020-05-22T16:21:04ZS-EPMC71147543225848410.1016/j.heliyon.2020.e03639