{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["51(10)"],"submitter":["Pilatz A"],"funding":["This work was supported by the LOEWE focus group MIBIE (Male Infertility during Infection and Inflammation, projects B1, C1, C2, and C3, state government of Hessen, Germany). None of those who provided funds had a role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript."],"pubmed_abstract":["Considering infection/inflammation to be an important risk factor in male infertility, the aim of this study was to make a comprehensive evaluation of the prevalence of urogenital tract infection/inflammation and its potential impact on sperm retrieval in azoospermic patients. In this prospective study, 71 patients with azoospermia were subjected to an extensive andrological workup including comprehensive microbiological diagnostics (2-glass test, semen, testicular swab and testicular tissue analysis) and testicular biopsy/testicular sperm extraction (TESE). Medical history suggested urogenital tract infection/inflammation in 7% of patients, 11% harboured STIs, 14% showed significant bacteriospermia, 15% had seminal inflammation, 17% fulfilled the MAGI definition, and 27% had relevant path"],"journal":["Andrologia"],"pagination":["e13401"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7147116"],"repository":["biostudies-literature"],"pubmed_title":["High prevalence of urogenital infection/inflammation in patients with azoospermia does not impede surgical sperm retrieval."],"pmcid":["PMC7147116"],"pubmed_authors":["Pilatz A","Weidner W","Schuppe HC","Kaplan H","Hossain H","Schuttler CG","Bergmann M","Diemer T","Fietz D","Domann E","Kilb J","Wagenlehner F"],"additional_accession":[]},"is_claimable":false,"name":"High prevalence of urogenital infection/inflammation in patients with azoospermia does not impede surgical sperm retrieval.","description":"Considering infection/inflammation to be an important risk factor in male infertility, the aim of this study was to make a comprehensive evaluation of the prevalence of urogenital tract infection/inflammation and its potential impact on sperm retrieval in azoospermic patients. In this prospective study, 71 patients with azoospermia were subjected to an extensive andrological workup including comprehensive microbiological diagnostics (2-glass test, semen, testicular swab and testicular tissue analysis) and testicular biopsy/testicular sperm extraction (TESE). Medical history suggested urogenital tract infection/inflammation in 7% of patients, 11% harboured STIs, 14% showed significant bacteriospermia, 15% had seminal inflammation, 17% fulfilled the MAGI definition, and 27% had relevant path","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Nov","modification":"2025-04-18T21:12:51.232Z","creation":"2020-05-22T16:47:57Z"},"accession":"S-EPMC7147116","cross_references":{"pubmed":["31456226"],"doi":["10.1111/and.13401"]}}