biostudies-literatureOrbai AMJerome L. Greene FoundationPfizerNational Institute for Health Research (NIHR)NIAMS NIH HHS1772-1779https://www.ebi.ac.uk/biostudies/studies/S-EPMC7153974biostudies-literatureUnknown72(12)<h4>Objective</h4>Sex differences may modify symptoms, disease expression, and treatment effects. The objective of this study was to evaluate the link between life impact and sex in psoriatic arthritis (PsA).<h4>Methods</h4>Remission and Flare in Psoriatic Arthritis (ReFlaP; ClinicalTrials.gov identifier: NCT03119805) was a study in 14 countries of consecutive adult patients with definite PsA. Participants underwent comprehensive PsA assessment using the following measures: Disease Activity in Psoriatic Arthritis (DAPSA), Minimal Disease Activity (MDA), and Psoriatic Arthritis Impact of Disease (PsAID). Disease activity was compared by sex using t-tests or Wilcoxon tests. The association of PsAID with sex was analyzed using hierarchical generalized linear models.<h4>Results</h4>Of 458 partArthritis care & researchDeterminants of Patient-Reported Psoriatic Arthritis Impact of Disease: An Analysis of the Association With Sex in 458 Patients From Fourteen Countries.PMC7153974Jerome L Greene Foundation ScholarCL-2011-02-001CS-2016-16-016P30 AR070254Orbai AMKalyoncu UKiltz UDernis EScrivo RAydin SCanete JDRichette PPerin JGorlier Cde Wit MCoates LCPalominos PERuyssen-Witrand AEder LLeung YYTalli SSmolen JSGaydukova IGossec LSoubrier MLubrano EHusni MEBalanescu AfalseDeterminants of Patient-Reported Psoriatic Arthritis Impact of Disease: An Analysis of the Association With Sex in 458 Patients From Fourteen Countries.<h4>Objective</h4>Sex differences may modify symptoms, disease expression, and treatment effects. The objective of this study was to evaluate the link between life impact and sex in psoriatic arthritis (PsA).<h4>Methods</h4>Remission and Flare in Psoriatic Arthritis (ReFlaP; ClinicalTrials.gov identifier: NCT03119805) was a study in 14 countries of consecutive adult patients with definite PsA. Participants underwent comprehensive PsA assessment using the following measures: Disease Activity in Psoriatic Arthritis (DAPSA), Minimal Disease Activity (MDA), and Psoriatic Arthritis Impact of Disease (PsAID). Disease activity was compared by sex using t-tests or Wilcoxon tests. The association of PsAID with sex was analyzed using hierarchical generalized linear models.<h4>Results</h4>Of 458 part2020-01-01T00:00:00Z2020 Dec2026-05-02T11:45:39.204Z2022-02-11T13:21:45.134ZS-EPMC71539743160952510.1002/acr.24090