{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ha HJ"],"funding":["Radiation Technology R&amp;amp;D program through the National Research Foundation of Korea funded by the Ministry of Science, ICT &amp;amp; Future Planning, Republic of Korea.","Radiation Technology R&D program through the National Research Foundation of Korea funded by the Ministry of Science, ICT & Future Planning, Republic of Korea."],"pagination":["E387"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7154805"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(3)"],"pubmed_abstract":["Calnexin (CNX) is an integral membrane protein that functions as a chaperone in the endoplasmic reticulum for the correct folding of proteins under stress conditions, rendering organisms tolerant under adverse conditions. Studies have investigated the cytogenetic effects of gamma irradiation (Ɣ-IR) on plants, but information on the molecular response under Ɣ-IR remains limited. Previously, we constructed a cDNA library of an irradiation-sensitive bioindicator plant, <i>Tradescantia</i> BNL4430 (T-4430) under Ɣ-IR, in which the <i>Calnexin-1</i> gene was highly upregulated at 50 mGy treatment. <i>TrCNX1</i> encodes a 61.4 kDa protein with conserved signature motifs similar to already reported <i>CNX1</i>s. <i>TrCNX1</i> expression was evaluated by semiquantitative reverse transcriptase PCR "],"journal":["Plants (Basel, Switzerland)"],"pubmed_title":["Molecular Characterization and Identification of <i>Calnexin 1</i> As a Radiation Biomarker from <i>Tradescantia</i> BNL4430."],"pmcid":["PMC7154805"],"funding_grant_id":["NRF-2013M2A2A6043621"],"pubmed_authors":["Kang SY","Ha HJ","Lee GJ","Subburaj S","Kim JB","Kim YS"],"additional_accession":[]},"is_claimable":false,"name":"Molecular Characterization and Identification of <i>Calnexin 1</i> As a Radiation Biomarker from <i>Tradescantia</i> BNL4430.","description":"Calnexin (CNX) is an integral membrane protein that functions as a chaperone in the endoplasmic reticulum for the correct folding of proteins under stress conditions, rendering organisms tolerant under adverse conditions. Studies have investigated the cytogenetic effects of gamma irradiation (Ɣ-IR) on plants, but information on the molecular response under Ɣ-IR remains limited. Previously, we constructed a cDNA library of an irradiation-sensitive bioindicator plant, <i>Tradescantia</i> BNL4430 (T-4430) under Ɣ-IR, in which the <i>Calnexin-1</i> gene was highly upregulated at 50 mGy treatment. <i>TrCNX1</i> encodes a 61.4 kDa protein with conserved signature motifs similar to already reported <i>CNX1</i>s. <i>TrCNX1</i> expression was evaluated by semiquantitative reverse transcriptase PCR ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Mar","modification":"2026-05-02T05:37:34.705Z","creation":"2020-05-22T17:41:46Z"},"accession":"S-EPMC7154805","cross_references":{"pubmed":["32245094"],"doi":["10.3390/plants9030387"]}}