biostudies-literatureUnknown2020Teshima KWe report a case of a 74-year-old man with a cluster of differentiation (CD) 7-positive diffuse large B-cell lymphoma (DLBCL) in the right nasal cavity. Flow cytometry analyses showed CD7 and CD20 positivity in tumor cells. The patient received 6 cycles of R-CHOP plus local radiation therapy because positron emission tomography-computed tomography after R-CHOP revealed an intranasal lesion. The patient achieved complete remission (CR) after radiation therapy. The frequency of CD7-positive DLBCL is rare, and only 11 cases with follow-up of clinical course have been reported thus far. CR or partial response was noted in 8 of 11 cases after receiving rituximab combined with chemotherapy. In total, 9 of 12 cases involved the development of extranodal lesions, which occurred as an intranasal tumor in 3 cases. It is important to examine the clinical features by accumulation of further cases.Case reports in hematology1514729https://www.ebi.ac.uk/biostudies/studies/S-EPMC7174964biostudies-literatureCD7-Positive Diffuse Large B-Cell Lymphoma Presenting as an Intranasal Tumor.PMC7174964Saito TKubota YEnomoto YMiura MTeshima KIkeda SSaito KSaito MAbe KOhyagi HZuguchi MKume MTakahashi SKawaharada YTakahashi NfalseCD7-Positive Diffuse Large B-Cell Lymphoma Presenting as an Intranasal Tumor.We report a case of a 74-year-old man with a cluster of differentiation (CD) 7-positive diffuse large B-cell lymphoma (DLBCL) in the right nasal cavity. Flow cytometry analyses showed CD7 and CD20 positivity in tumor cells. The patient received 6 cycles of R-CHOP plus local radiation therapy because positron emission tomography-computed tomography after R-CHOP revealed an intranasal lesion. The patient achieved complete remission (CR) after radiation therapy. The frequency of CD7-positive DLBCL is rare, and only 11 cases with follow-up of clinical course have been reported thus far. CR or partial response was noted in 8 of 11 cases after receiving rituximab combined with chemotherapy. In total, 9 of 12 cases involved the development of extranodal lesions, which occurred as an intranasal tumor in 3 cases. It is important to examine the clinical features by accumulation of further cases.2020-01-01T00:00:00Z2020 2020-05-22T18:22:25Z2020-05-22T18:22:25ZS-EPMC71749643232832010.1155/2020/1514729