{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Akpa OM"],"funding":["NIDDK NIH HHS","NHGRI NIH HHS","NINDS NIH HHS","Wellcome Trust"],"pagination":["1167-1178"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7176339"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["75(5)"],"pubmed_abstract":["Hypertension and obesity are the most important modifiable risk factors for cardiovascular diseases, but their association is not well characterized in Africa. We investigated regional patterns and association of obesity with hypertension among 30 044 continental Africans. We harmonized data on hypertension (defined as previous diagnosis/use of antihypertensive drugs or blood pressure [BP]≥140/90 mmHg/BP≥130/80 mmHg) and obesity from 30 044 individuals in the Cardiovascular H3Africa Innovation Resource across 13 African countries. We analyzed data from population-based controls and the Entire Harmonized Dataset. Age-adjusted and crude proportions of hypertension were compared regionally, across sex, and between hypertension definitions. Logit generalized estimating equation was used to det"],"journal":["Hypertension (Dallas, Tex. : 1979)"],"pubmed_title":["Regional Patterns and Association Between Obesity and Hypertension in Africa: Evidence From the H3Africa CHAIR Study."],"pmcid":["PMC7176339"],"funding_grant_id":["099313/B/12/Z","U54 HG006938","U54 HG006947","U01 HG010273","R01 NS107900","U54 DK116913","U54 HG006939","U54 HG007479","099313/Z/12/Z"],"pubmed_authors":["Akpa OM","Agongo G","Norris SA","Ramsay M","as members of the CVD Working Group of the H3Africa Consortium","Alberts M","Parekh RS","Mensah GA","Akinyemi R","Chishala C","Engel ME","Sarfo F","Mohamed SF","Wiley K","Gomez-Olive FX","Sorgho H","Wahab K","Ekoru K","Tollman S","Mayosi BM","Tayo B","Peprah E","Boua RP","Owolabi MO","Waddy SP","Made F","Ovbiagele B","Asiki G","Rotimi C","Motala AA","Troyer J","Adu D","Micklesfield L","Nonterah EA","Salako B","Mashinya F","Gebregziabher M","Ali SA","Ojo A","Adebamowo SN"],"additional_accession":[]},"is_claimable":false,"name":"Regional Patterns and Association Between Obesity and Hypertension in Africa: Evidence From the H3Africa CHAIR Study.","description":"Hypertension and obesity are the most important modifiable risk factors for cardiovascular diseases, but their association is not well characterized in Africa. We investigated regional patterns and association of obesity with hypertension among 30 044 continental Africans. We harmonized data on hypertension (defined as previous diagnosis/use of antihypertensive drugs or blood pressure [BP]≥140/90 mmHg/BP≥130/80 mmHg) and obesity from 30 044 individuals in the Cardiovascular H3Africa Innovation Resource across 13 African countries. We analyzed data from population-based controls and the Entire Harmonized Dataset. Age-adjusted and crude proportions of hypertension were compared regionally, across sex, and between hypertension definitions. Logit generalized estimating equation was used to det","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 May","modification":"2025-04-21T23:06:40.661Z","creation":"2020-05-22T19:09:02Z"},"accession":"S-EPMC7176339","cross_references":{"pubmed":["32172619"],"doi":["10.1161/HYPERTENSIONAHA.119.14147"]}}